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Articles by K.Y. Musa
Total Records ( 3 ) for K.Y. Musa
  H. Musa , I.A. Yakasai , K.Y. Musa , A.B. Isah and K. Mshelbwala
  The objective of this research is to determine the concentration of arsenic in wells and boreholes water in Zaria, to see whether the concentration level is sufficient enough to affect the health of the people living in the area under study. In this study arsenic concentrations of sixty well and five bore hole water samples collected from Zaria and environs were determined using standard procedures. The results obtained shows that arsenic concentrations ranged from <0.002 to 0.51 mg L-1, with 75% of the samples above the World Health Organization drinking water guideline. Bore whole water samples were found to contain less arsenic compared with the shallow well water samples studied. Most wells and boreholes in Zaria were found to be contaminated with abnormal concentration of arsenic sufficient enough to cause serious health hazards to the users.
  K.Y. Musa , A. Ahmed , G. Ibrahim , O.E. Ojonugwa , M. Bisalla , H. Musa and U.H. Danmalam
  Toxicity studies on the methanolic extract of Portulaca oleracea L. were carried out on mice intraperitoneally. The LD50 was calculated using the methods of Miller and Tainter (LD50, 1853.5 mg kg-1), Reed and Muench (LD50, 1871 mg kg-1) and Karber method (LD50, 1875 mg kg-1) these values placed the plant to be moderately toxic. Histopathological findings revealed that the extract has effect on the kidney, lung and liver in a dose dependent manner.
  G. Ibrahim , S. Abdulmumin , K.Y. Musa and A.H. Yaro
  The anticonvulsant effects of the crude flavonoid fraction of the stem bark of Ficus sycomorus were studied using the subcutaneous Pentylenetetrazole (PTZ) and Maximal Electroshock Test (MEST) models in mice and chicks respectively. The crude flavonoid fraction exhibited a significant (p<0.05) latency in mean onset and mean time of death of convulsed animal with a 20% protection at a dose of 10 mg kg-1 body weight i.p. (comparable to Valproic acid at 200 mg kg-1) while it showed a significant (p<0.05) and dose dependent maximal protection (83.3%) in the Maximal Electroshock Test (MEST) at an optimal dose of 20 mg kg-1 body weight i.p. (comparable to Phenytoin at 20 mg kg-1). The results obtained supported the claim in the traditional use of the stem bark of the plant in the management of epilepsy.
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