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Articles by K. Ganesan
Total Records ( 3 ) for K. Ganesan
  S. Bragadeeswaran , K. Ganesan and N. Sri Kumaran
  Ascidians are marine animals with a great ability to synthesize bioactive substances. This study examined the heamolytic potential of ascidians Polyclinum madrasensis and Phallusia nigra. Ascidians P. madrasensis and P. nigra were collected from Tuticorin, Southeast coast of India. The collected ascidians were extracted by methanol at room temperature. The solvents were removed under reduced pressure to give predominantly an aqueous suspension. The protein content of crude P. madrasensis showed 680 μg mL-1 and crude P. nigra showed 543 μg mL-1, respectively. In sodium dodecyl sulfate polyacrylamide gel electrophoresis crude protein of P. madrasensis showed 4 bands 20, 27, 37 and 50 kDa and P. nigra showed 3 bands 20, 37 and 50 kDa. In the hemolytic assay maximum activity 64 Hemolytic Unit was showed in human “B” erythrocytes by P. madrasensis extract and minimum 2 Hemolytic Unit in human ‘O’ erythrocytes by crude extract of P. madrasensis. In 1H-NMR spectrum the spectral signal at δ 8.1 and δ 7.9 indicates the presence of guanidine and thymidine containing alkaloid in P. madrasensis and P. nigra. Thus results proved that the ascidians have remarkable hemolytic compounds and further studies will fulfill for purification and structural elucidation of the compounds.
  K. Ganesan and G. Siva
  Local language computing is essential for developing nations like India, as these countries are diversified by languages and this diversity of languages is the barrier for the penetration of digital revolution. We propose a new methodology called Multilingual Querying and Information Processing that provides multilingual processing functionality for some of the real world deployments like relational database systems. We propose a way of processing multilingual information wherein the back end uses English language and the front end uses local language like Tamil. The processing of the front end has the capability to display multilingual information. Our implementation is flexible enough to deploy the query processing and information retrieval systems. In this study, we present our approach to implement the above methodology.
  K. Ganesan and V. Palanisamy
  In this study, researchers present the design, analysis and fabrication of MEMS based silicon micro-needles for insertion of fluid into the dermis and subcutaneous fat layer of human skin. Microelectromechanical Systems (MEMS) are uncovered to an assortment of liquid environments in applications such as chemical and biological sensors and microfluidic devices. In this study, the design and fabrication of a multi-material high-performance micropump is presented. The fabrication process using MEMS fabrication techniques, comprised of silicon and pyrex micromachining and bonding. Manufacturing steps such as three small bulk cylindrical piezoelectric material elements that are integrated with micro-fabricated Silicon-On-Insulator (SOI) and glass micromachined substrates using eutectic bonding and anodic bonding processes were successfully realized and provide a robust and scalable production technique for the micro pump. Exceptional flow rates of 0.1 mL min-1 with 1 W power consumption based on piezoelectric stack actuation achieved by appropriate design optimization. The analysis forecasts that the resultant stresses due to applied meandering and axial loads are in the safe range below the acquiesce strength of the material.
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