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Articles by K. Eklu-Gadegbeku
Total Records ( 3 ) for K. Eklu-Gadegbeku
  K. Tona , A. Agbonon , K. Eklu-Gadegbeku , A. Teteh , P. Simons , J. Buyse , N. Everaert , B. Kemp , E. Decuypere and M. Gbeassor
  In commercial poultry husbandry practice, the hatchery takes over the incubation of bird eggs in order to provide as many day-old chicks as needed at any time to farmers. The main bottleneck for poultry industry development in Togo is the lack of day-old chick supply. Indeed, there is no proficient hatchery which can cover the needs of the farmers because of lack of information about hatchery management or people trained as hatchery managers. Also, there is lack of information about management practice aspects, etc. With the aim to promote poultry industry in Togo, an interuniversity project [Catholic University of Leuven (KUL) and University of Lome (UL)] as a model of poultry industry development was implemented. Specific objectives of the current project are to implement research and development activities on better conditions of incubation and adapted management practices focusing mainly on (1) Effect of early transferring of layer breeders hatching eggs on embryo parameters and hatchability, (2) Comparison of different chicken genotypes in Embryo Physiology, (3) Effects of heat conditioning at d 16 to 18 of incubation or during early broiler rearing on embryo physiology, post-hatch growth performance and heat tolerance, (4) Effect of low albumen quantity on chick embryo and post-hatch parameters, (5) Effects of In ovo-administration of L-carnitine on hatching events and juvenile performance of layer-type chick, (6) Interaction effects of mixing hatching eggs of differential embryo growth trajectory and incubator CO2concentration on embryo physiological parameters, (7) Effect of delayed feed access on production and blood parameters of layer-type chicks and (8) Induced moulting of layer chickens.
  Lawson-Evi Povi , A.E. Motto , K. Atchou , K. Tona , K. Eklu-Gadegbeku and K. Aklikokou
  Background and Objective: Pterocarpus erinaceus (Fabaceae), Amaranthus spinosus (Amaranthaceae) and Anogeissus leiocarpus (Combretaceae) are plants used in the treatment of diabetes many times. The present study was undertaken to observe the insulinomimetic activity of a different type of plants. Materials and Methods: The hypoglycemic effect of hydroalcoholic extracts from the stem bark of P. erinaceus and the roots of A. spinosus and A. leiocarpus was evaluated in ovo on 11 days-old chicken embryos and ex vivo on skeletal muscles isolated from rats. Results: All extracts reduced significantly the chicken embryos basal glycemia in the treated groups compared to the control group at the doses of 0.03 and 0.06 mg/100 μL. The extract of A. leiocarpus (0.5 and 1 mg mL1) increased (p<0.001 and p<0.0001) the absorption of glucose by the muscle in the presence and absence of insulin more than the extracts of Pterocarpus erinaceus and Amaranthus spinosus. Conclusion: Hence, it was concluded that, the three extracts decreased the basal glycemia in ovo. Whereas the extract of A. leiocarpus has an effect, similar to an insulinomimetic effect.
  A. Missebukpo , K. Metowogo , A. Agbonon , K. Eklu-Gadegbeku , K. Aklikokou and M. Gbeassor
  Ixora coccinea L. (Rubiaceae) possess anti-inflammatory and antitussive properties. It is traditionally used for various respiratory ailments including catarrhal bronchitis cough and asthma. In the present study we investigated anti-asthmatic properties of an hydroalcoholic leaf extract of I. coccinea in an ovalbumin (OVA)-induced asthmatic rat model. We also evaluated the anti-allergic property of the extract by Abdominal Wall (AW) method and histamine-induced cutaneous reaction. Rats were sensitized with intraperitoneal (i.p.) ovalbumin and challenged by OVA intranasally to induce chronic airway inflammation. Randomized treatment groups of sensitized rats received I. coccinea extract or distilled water. I. coccinea extract at doses of 1000 and 1500 mg kg-1 suppressed eosinophilia and significantly inhibited AHR in rat with OVA-induced asthma. Based on lung histopathological study using hematoxylin and eosin I. coccinea reduced inflammatory cell infiltration and repaired epithelial cells damaged. In addition the extract at the same doses significantly decreased the diameter of the blue spot (16 and 55%, respectively) compared with the controls and inhibited the skin reactions induced by histamine (23.55 and 53.36%, respectively). In conclusion our results provide evidence that I. coccinea has anti-asthmatic properties and then can support its use in folk medicine to treat asthma.
 
 
 
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