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Articles by John Kateregga
Total Records ( 3 ) for John Kateregga
  Rebecca Nalubega , John David Kabasa , Deo Olila and John Kateregga
  This study evaluated the antibacterial activity of aqueous extracts of eleven plants against gram positive (Staphylococcus aureus, Streptococcus faecalis) and gram negative (Escherichia coli and Salmonella typhimurium) bacteria using the agar well diffusion assay and tube dilution method. Qualitative tests were carried out to investigate the phytochemical composition for ether, ethanol and aqueous extracts of these plants. In general, gram-positive bacteria were more susceptible than gram-negative bacterial species. The aqueous extract of Moringa oleifera had activity on all the four bacteria species. The aqueous extracts of Persea americana had the lowest MIC (0.25 g mL-1) and therefore, the best activity on Salmonella typhimurium. Leonotis nepetifolia with MIC (0.25 g mL-1) and Lantana trifolia with MIC (0.15 g mL-1) had the lowest MICs and therefore, the best activity on Staphylococcus aureus. The most prominent phytochemicals of medicinal importance established in the extracts of most test plants were tannins, sterols, basic alkaloids and alkaloid salts. These results suggest that Moringa oleifera extracts could be of value in the discovery of compounds which may be effective in the treatment of a number of bacterial diseases. Similarly, Persea americana extracts may contain active compounds that could be used for treatment of salmonellosis while Leonotis nepetifolia and Lantana trifolia may contain compounds effective against staphylococcal infections. All the 11 tested plants contain phytochemicals with potentially beneficial therapeutic effects.
  Rebecca Nalubega , John David Kabasa , Deo Olila and John Kateregga
  The antibacterial activity of ethanol and ether extracts of 30 medicinal plants used against poultry diseases in Masaka district of Uganda was evaluated. The extracts were tested against gram positive (Staphylococcus aureus, Streptococcus faecalis) and gram negative bacteria (Escherichia coli, Salmonella typhimurium) using the agar well diffusion assay. Both ethanol and ether extracts showed activity (100 and 97%, respectively) against at least one bacterium. In general, gram positive bacteria were more susceptible than gram negative bacterial species. Of the four bacteria species, Staphylococcus aureus was the most susceptible to both extracts. These results therefore suggest that these plants can be used to provide lead compounds which can be used in the discovery of new antibacterials.
  Rebecca Nalubega , John David Kabasa , Deo Olila and John Kateregga
  The objective of this field survey was to identify and document knowledge about the plants which are used in the prophylaxis and treatment of poultry diseases in Kyanamukaka and Buwunga sub-counties of Masaka district of Central Uganda. Focus group discussions and key informant interviews were conducted. Plants were ranked according to the frequency of use. Fifty nine plant species from 33 families were found to be used in the treatment of a variety of poultry diseases in this area. Family Asteraceae had the highest number of plant species used (30%) and leaves were the most commonly used parts of the plants (80%). The most frequently used plants were Cannabis sativa and Nicotiana tobaccum. Most of the plants were used for prophylaxis (68%) and the oral route was the most preferred route of administration (96%). The results of this study will contribute to ensuring that this knowledge is passed on to other generations and will serve as a basis in the search for newer pharmaceuticals.
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