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Articles by Jing Sun
Total Records ( 9 ) for Jing Sun
  Jing Sun and Aiping Yang
  This study aims to provide a scientific inbound processing method for express companies to standardize their operation thus improve their service quality consistently. The general guidelines in respect to safety, clothing and planning ahead are listed and effective sorting and loading methods are discussed in detail. The inbound processing method provides couriers a good and timely start of shift with the proper workload assign to them which ensures express companies improve reliability, safety and productivity.
  Jing Sun and Shaohua Dong
  Rapid increasing logistics demands call for high efficiency delivery in cities. Effective city planning of distribution centers is crucial. This paper describes the steps of distribution centers planning in detail including zone definition, shipment volume forecast, productivity forecast and capacity forecast. Based on these data, the author puts forward an effective way to build and evaluate operation models. Proper implementation of the best operation model will be helpful to fulfill the increasing market requirements.
  Umair Muhammad , Xiaoyu Zhu , Zhaoxin Lu , Jinzhi Han , Jing Sun , Sultana Tayyaba , Benazir Abbasi , Farman Ali Siyal , Kuldeep Dhama and Jabbar Saqib
  Background and Objective: Vine tea (Ampelopsis grossedentata) may potentially perform multiple pharmacological roles, including antibacterial, anti-cancer, antioxidant, hepatoprotective and anti-hypertension functions. But effects of extraction polarity, time and temperature on the recovery of bioactive compounds along their pharmacological activity of vine tea extract have not been reported yet. The present study reports on the importance of extraction variables for obtaining vine tea extract aiding in purification and isolation of functional and polyphenolic compound and their pharmacological activity (polyphenols) from vine tea. Materials and Methods: The effects of extraction variables (time, temperature and polarity) on Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and Condensed Tannin Content (CTC) were evaluated using single factor experiment. Antiradical capacity assay and radical-scavenging capacity 2,2-diphenyl-1-picrylhydrazyl (DPPH) were tested for evaluating the antioxidant activities of vine tea crude extract. To analyze data, one-way analysis of variance (ANOVA) was established followed by the Tukey’s test and to test the correlation, Pearson correlation coefficient was tested. Results: Data explained that extraction polarity, extraction time and the temperature had a significant effect (p<0.05) on yield and their anti-radical activities. The optimized extraction parameters for TFA and CTC were 40% aqueous ethanol at 45 while 50 for TPC for 180 min. Whereas, maximum yield were 40.01 μg Catechin Equivalent per gram (CE g–1) of Dry Weight (DW) for TFA, 15.12 μg, Gallic Acid Equivalent per gram of DW (GAE g–1) for TPC and 12.70 μg CE g–1 DW for CTC. Ethanol concentration showed a significant effect (p<0.05) on extraction of phenolic compounds and their pharmacological activity especially antioxidant capacity and DPPH assay. Conclusion: This study showed that extraction variables were greatly influence on the pharmacological activities of vine tea crude extract and this study can be used as preliminary and key information to design central composite rotatable design for Response Surface Methodology (RSM). Moreover, this approach can be used to determine significant factors that influence functional compounds and their other pharmacological activities.
  Jing Sun and Shaohua Dong
  This study aims to introduce a method for better configuration of delivery area so as to increase the delivery efficiency at lower cost. Key delivery performance indicators are introduced. Objectives and expected outputs of Delivery Area Optimization and Management (DAOM) are analysed. Then the paper goes in detail to the four main steps of DAOM. Successful implementation of this process and usage of effective tools for ongoing management would bring benefits to corporate with respect to service quality and competitiveness.
  Hongmai Wu , Jing Sun , Hui Wang , Chumeng Lv , Rong Li , Xin Shi and Jian Ding
  This study mainly focus on: with the modern manufacturing industry stepping into the era of post-industrialization, Chinese modern manufacturing enterprises have to promote technical innovation, adjust industrial structures, perfect Logistics Resources System (LRS), strengthen quality education, enhance Supply Chain Management (SCM) level, fulfill energy saving and waste lowering, uphold stable, sustained and coordinated and scientific development. Facing to the global and economic recovery, this is a very important problem how to solve before us. Utilization of the production line balancing based on LRS integration, the Chinese modern manufacturing industry and logistics industry would put their heads together and find ways to tide over the difficulty and win an advantage over the international competition.
  Hui Wang , Hongmai Wu , Jing Sun and Guang Cheng
  This article is based on the method of equipment management business process reengineering as the research object and aiming at how to model and optimize equipment management business process. Business process reengineering of equipment management is Using quantitative analysis method, through the design structure matrix theory and calculation method of fuzzy mathematics and building the structure matrix business process model, clustering, combined with the theory of business process reengineering and method. It is verified through the spare parts from the business process and equipment and strengthened the connection between each business links, so as to reducing the waiting time which lays the theoretical foundation for the integration of management and information technology equipment management in informationization construction.
  Yan Zhang , Cheng-Gang Zhu , Rui-Xia Xu , Sha Li , Yuan-Lin Guo , Jing Sun and Jian-Jun Li
 

Background

Both proprotein convertase subtilisin/kexin type 9 (PCSK9) and fibrinogen have been established as novel markers for atherosclerotic diseases. However, no data are available regarding the relationship between circulating PCSK9 and fibrinogen concentration up to now.

Objective

To explore the potential link of the circulating PCSK9 concentration to fibrinogen in patients with stable coronary artery disease (CAD).

Methods

We studied 219 eligible consecutive patients with angiographically proven stable CAD. Baseline clinical and laboratory data were collected. Plasma PCSK9 concentration was measured by enzyme-linked immunosorbent assay. High-sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate, D-dimer, and albumin were also measured in all subjects as inflammatory markers. The relation of the circulating PCSK9 concentration to fibrinogen was evaluated.

Results

The data indicated that the patients with high PCSK9 concentration tended to have higher fibrinogen levels according to PCSK9 tertiles (P = .037). Spearman correlation analysis revealed a positive relation between plasma PCSK9 concentration and fibrinogen (r = 0.211, P = .002). Additionally, the circulating PCSK9 concentration also correlated positively with total cholesterol, low-density lipoprotein cholesterol, and hs-CRP levels (r = 0.333, P < .001; r = 0.302, P < .001; r = 0.153, P = .023, respectively). In the stepwise multivariate regression analysis, the association between PCSK9 and fibrinogen remained significant (β = 0.168, P = .011) after adjustment for conventional cardiovascular risk factors including lipid profiles, hs-CRP, and D-dimer.

Conclusion

The present study first demonstrated that the circulating PCSK9 concentration was positively associated with fibrinogen in patients with stable CAD, suggesting that the interactions of PCSK9 and fibrinogen in the status of atherosclerosis may need further investigation.

  Jing Sun , Shu-Yi Deng , Li Zhang , Juan He , Long Jiang , Zong-Wan Mao and Liang-Nian Ji
  Two copper(II) complexes with naphthalene ring [Cu(L1)(H2O)](ClO4)2 · H2O (1) or [Cu2(L2)(ClO4)(H2O)3](ClO4)3 · H2O (2) (L1 = 1-[bis(pyridine-2-ylmethyl)aminomethyl]naphthalene and L2 = 1,4-di[bis(pyridine-2-ylmethyl)aminomethyl]naphthalene) were synthesized. Structural characterization of complex 2 by X-ray crystallography showed that the cations form a double-forficiform structure and each Cu(II) ion is bound by an in-plane N3Ow-coordination. Thermal melting curves and fluorescence spectroscopes of complex-DNA binding indicate that both complexes can efficiently interact with calf thymus DNA and that the binding ability of complex 2 is greater than that of complex 1. Viscosity measurements suggest that complex 2 partially intercalates between DNA base pairs via the naphthalene ring, whereas complex 1 most likely interacts with DNA through the electrostatic binding. In the presence of H2O2 and ascorbic acid, dinuclear complex 2 was more efficient than mononuclear complex 1 in cleaving double-stranded circular DNA into linear DNA. The interaction modes between the complexes and DNA were also discussed.
  Jinchao Zhang , Cuilian Liu , Jing Sun , Dandan Liu and Peng Wang
  The effects of water extract of Cajanus cajan (Linn.) Millsp. (Leguminosae) leaves (WECML) on the osteogenic and adipogenic differentiation of mouse primary bone marrow stromal cells (BMSCs) and the adipocytic trans-differentiation of mouse primary osteoblasts (OBs) were studied. The results indicated that WECML promoted the proliferation of BMSCs and OBs at most concentrations. WECML promoted the osteogenic differentiation and formation of mineralized matrix nodules of BMSCs at concentrations of 0.1, 1, and 10 μg/mL, but inhibited the osteogenic differentiation and formation of mineralized matrix nodules of BMSCs at concentration of 0.01 μg/mL. WECML inhibited the adipogenic differentiation of BMSCs and adipocytic trans-differentiation of OBs at concentrations of 0.001, 0.1, 1, 10, and 100 μg/mL, but had no effects at concentration of 0.01 μg/mL. The results suggest that WECML has protective effects on bone and these protective effects may be mediated by decreasing adipocytic cell formation from BMSCs, which may promote the proliferation, differentiation, and mineralization function of OBs. The defined active ingredients in the WECML and the active mechanism need to be further studied.
 
 
 
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