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Articles by James F. Tobin
Total Records ( 1 ) for James F. Tobin
  Yan-ling Zhang , James F. Tobin and David V. Erbe
  PTP1b is clearly involved in attenuating signaling by both insulin and leptin, prompting much effort towards the development of inhibitors of this enzyme as therapeutics to treat type 2 diabetes and obesity. In this mini-review, we discussed the physicochemical nature of the PTP1b active site and how this poses challenges for drug design.
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