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Articles by J.S. Neils
Total Records ( 3 ) for J.S. Neils
  J.S. Neils , C. Augustine , D.I. Mojaba and U.I. Dazala
  The effect of processed Cassia obtusifolia seed meal as a replacement of protein on blood biochemistry (protein, albumin, globulin, Creatinine and cholesterol) was studied. One hundred and twenty (120) day old broilers chicks purchased from reputable source were randomly divided into four dietary treatments in a Randomized Complete Block Design (RCBD) with three replicates of ten birds each. Four experimental feeds were compounded with processed Cassia obtusifolia seed meal as replacement for protein at concentrations of 0, 2.5, 5.0 and 7.5% inclusion. The groups are as T1, T2, T3 and T4 groups, respectively, where T1 served as control. The experimental diet was fed to the birds for a period of 8 weeks. T2 (2.5%) and T3 (5.0%) groups had normal blood biochemical parameters while T4 (7.5%) did give normal range of biochemical values except for cholesterol level (172.86mg). The increase showed a level of significance (P<0.05) when compared to the normal range (52-148mg). The increase came from the high concentration (7.5%) of seed meal in feed (T4) in that T1 which was fed the conventional feed (control) did not show any change in the level of cholesterol. However, change in the concentration of cholesterol occurred with inclusion of Cassia Obtusifolia seed meal was made at higher percentage 7.5%, T4. This means that the level of cholesterol in chickens would be increased and becomes a risk factor to those who have preference for broiler meat. However, further investigations need to be carried out on the processing methods of Cassia obtusifolia seed that could enhance inclusion of seed meal beyond 7.5% with lesser risk of cholesterol build up in birds.
  J.S. Neils , E.O. Balogun , A.K.B. Sackey , U.S. Abdullahi and K.A.N. Esievo
  The concentration change of pyruvate was studied in serum of uninfected and infected sheep with T. congolense. In the uninfected, the mean concentration of 61.23-76.63 mg L-1 of pyruvate was determined using the DNS method. There was a depressed concentration of pyruvate in the two infected groups (A and B); pyruvate level fell to 25.7 mg L-1 in gp A that was treated immediately after the first peak of parasitaemia while in gp B, the concentrations continued to fall (5.2 mg L-1) until the termination of the experiment. The fall might have been as a result of the utilization of the pyruvate by either the host or its conversion to other compounds. It is therefore concluded that animals use the pyruvate or its converted to another compound during trypanosome infection. The decrease in pyruvate levels may be a possible cause of weakness and eventual death in infected animals.
  J.S. Neils , A.K. BSackey , U.S. Abdullahi and K.A.N. Esievo
  Yankassa sheep (20) were grouped into A and B and infected with Trypanosoma congolense isolated from a cow and maintained in mice. Two milliliterx107 parasites were used to infect group A. The course of the infection and serum trace minerals (Iron, (Fe) and Copper, (Cu) were studied and determined using Atomic Absorption Spectrophotometer (AAS). There was significant drop in concentration of iron (p<0.001) Post Infection (pi) while that of copper, no significant change (p>0.05). The values of the contemporaneously uninfected control sheep were significantly higher for iron and not for copper. Sheep are susceptible to isolate from cow and passaged in mice and with the fluctuating concentrations of Fe and consistency of Cu, it may suggest that these minerals may have a role in the pathogenesis of trypanosomosis due to T. congolense.
 
 
 
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