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Articles by J.S. Chen
Total Records ( 2 ) for J.S. Chen
  J.S. Chen , R.F. Zhu , Y.X. Zhang , S. Chen , C. Gao and D.G. Li
  A defoliation experiment was conducted on a Leymus chinensis-dominated steppe to provide guidelines of grazing management and restoration of degraded grasslands. There were five defoliation treatments: CK (non-defoliation as control); LD (Light Defoliation, cut 12 cm aboveground level); MD (Medium Defoliation, 8 cm); HD (Hard Defoliation, 4 cm) and SD (Severe Defoliation, 2 cm). Results showed that HD and SD defoliation significantly decreased the belowground biomass. Defoliation increased plant species diversity but decreased biomass of L. chinensis significantly. The biomass of L. chinensis under LD was lower than that in control indicating L. chinensis was highly sensitive to defoliation. It is necessary in this area that grazing should be restricted to a level of light defoliation to prevent loss of plant productivity.
  S.M. Ji , L.S. Li , J.Q. Wen , G.Z. Sha , Z. Cheng , D.R. Cheng , J.S. Chen and Z.H. Liu
  Sirolimus (SRL) is a potent immunosuppressive drug used to prevent acute allograft rejection after renal transplantation. Nevertheless, the occurrence of proteinuria has recently been recognized among patients on SRL-based therapy. The aim of this study was to investigate the therapeutic effects of Tripterygium wilfordii Hook F. (T II) on proteinuria associated with SRL in renal transplant recipients. According to accepting T II, 36 recipients were divided into 2 groups: T II group (n = 21) and valsartan group (n = 15). The T II group was administered 1 mg/kg/d, and the valsartan group, 80 mg twice per day for 12 months. Efficiency was then evaluated. Complete remission: proteinuria decreased by >50%; partial remission: proteinuria decreased by 20% to 50%; ineffective: proteinuria decreased by <20%. Upon 12-month follow-up, the total effective rates in the T II group and the valsartan group were 95.2% and 86.7% (P < .05), respectively. Twenty of 21 patients with proteinuria in the T II group were negative at 3-month follow-up with disappearance of edema. There were some adverse events that had greater incidence rates in the valsartan group compared with the T II group, such as hyperkalemia (26.7% vs 4.8%). We concluded that the application of T II markedly reduced proteinuria associated with SRL in renal transplant patients.
 
 
 
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