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Articles by J.A. Akinyanju
Total Records ( 3 ) for J.A. Akinyanju
  S.A. Laleye , A.P. Igbakin and J.A. Akinyanju
  The effect of Nono (a Nigerian fermented milk) on diabetic situation in rats, induced by intraperitonial injection of alloxan monohydrate is reported. Nono administration for 4 weeks lowered the raised plasma glucose concentration of diabetic rats; restoring it to the non diabetic rat level. The low tissue protein and raised plasma protein concentrations; hyperlipidemia; and hypercholesterolemia consequential on diabetic induction were reversed to the normal level by the Nono administration. The reversals of these effects of diabetes may be due to the lowering of the plasma glucose concentration by Nono or direct activity of either the bacteria or milk components of Nono on these substances. The results indicate that consumption of Nono produced by wild strain lactic acid bacteria may be helpful in the management of diabetes.
  A.S. Adegoke , J.A. Akinyanju and J.E. Olajide
  White dent maize was sorted manually into apparently clean and visibly spoilt maize samples. The maize samples were pulverized and fermented for Ogi production. The clean and spoilt maize samples had 11.8 and 18.6% moisture content, respectively. During fermentation, the concentration of aflatoxin B present in the apparently clean white dent maize slurry rose from 0.98 μg mL-1 at day 0-1.05 μg mL-1 at day 1 while for visibly spoilt white dent maize slurry the concentration rose from 2.20 μg mL-1 at day 0-2.55 μg mL-1 at day 1. The study also shows the persistence of aflatoxin B throughout the fermentation period with concentrations remaining at 1.05 and 2.55 μg mL-1, respectively for both samples. Fermentation was accompanied with decrease in pH of the slurry from 6.0 at day 0-4.0 at day 3 for apparently clean white dent maize slurry and 5.8 at day 0-4.0 at day 3 for visibly spoilt white dent maize slurry. There was a corresponding increase in the titratable acidity from 0.2 at day 0-1.1 at day 3 and 0.4 at day 0-2.3 at day 3, respectively. This study shows a deleterious health hazard in the continuous use of aflatoxin B contaminated maize in Ogi production.
  G.I. Olasehinde , J.A. Akinyanju and A.A. Ajayi
  Studies were carried out to determine the disinfectant property of naphthol and its derivatives. The sensitivity of some clinical organisms as compared with the activity of some selected commercial disinfectants was tested. The methods employed for assessing the efficacy of disinfectants in this study are Minimal Inhibitory Concentration (MIC) Test and Capacity Use Dilution Test. The clinical organisms used for the tests are Pseudomonas aeruginosa, Salmonella typhi and Proteus mirabilis while the commercial disinfectants used are Dettol (Chloroxylenol), Savlon (Cetrimide/chlorhexidine mixture) and TCP (Trichlorophenol) and the Naphtholics are alpha naphthol and 2-amino-1,4-naphthoquinonimine hydrochloride. Dettol showed highest antibacterial activity against all the test organisms. Savlon`s antibacterial activity was high against the test organisms except Pseudomonas aeruginosa. TCP showed low activity against all the test organisms while Purified ∞-naphthol and its derivative, 2-amino-1, 4-naphthoquinonimine hydrochloride were found to exhibit disinfecting properties, with the derivative showing more antimicrobial activity than ∞-naphthol. The compounds have bactericidal effect against the test organisms used in this study.
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