Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by J. Bargujar
Total Records ( 1 ) for J. Bargujar
  N. Kataria , J. Bargujar , P.K. Pilania , N. Arya , T. Bhati , N. Mohammed , P. Nathawat , M. Mathur , S. Choudhary , S. Asopa , Abhimanu and A.K. Kataria
  To evaluate stress and metabolic adjustments in buffaloes with Post Parturient Haemoglobinuria (PPH), certain serum enzymes viz. Gamma-Glutamayl Transferase (GGT), Glucose-6-Phosphatase (Glc-6-Pase), aldolase, glucose-6-phosphate dehydrogenase, glutamate dehydrogenase, malate dehydrogenase, arginase and 5'nucleotidase enzymes were determined. Simultaneously haemoglobin and serum calcium, phosphorus, glucose and proteins were also determined. Blood samples were collected from adult female healthy and buffaloes with post parturient haemoglobinuria. In affected group the mean values of all the parameters were compared with respective healthy mean values. Significantly (p≤0.05) increased serum GGT activity in buffaloes with PPH indicated stress. Activities of the enzymes related to glycolysis and hexose monophosphate shunt were found to be decreased in affected animals. Activities of other enzymes like Glc-6-Pase, GDH, MDH, ARG and 5'NT were found increased significantly (p≤0.05) in the affected cases. This pattern was suggestive of metabolic adjustments where rate of glycolytic pathway decreased and rate of gluconeogenesis was observed to be increased in the affected cases. Correspondingly, serum glucose concentration of affected animals was significantly (p≤0.05) higher. Serum calcium showed non significant (p>0.05) difference whereas serum phosphorus, proteins and haemoglobin levels decreased significantly (p≤0.05) in affected cases. Decreased levels of phosphorus and disturbed calcium to phosphorus ratio suggested that phosphorous deficiency plays a key role in causing haemoglobinuria in buffaloes. Pattern of variation in the activities of the enzymes related to various metabolic processes revealed the metabolic adjustments. The data obtained in the present investigation support the concept that sustained PPH stress may represent an integrating mechanism underlying metabolic adjustments for homeostasis. Better understanding between PPH stress and metabolic homeostasis can be instrumental in the design of novel therapeutic strategies.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility