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Articles by J. W. Kim
Total Records ( 3 ) for J. W. Kim
  C. H Lee , J. H Mo , I. J Choi , H. J Lee , B. S Seo , D. Y Kim , P. Y Yun , I. Y Yoon , H Won Lee and J. W. Kim
 

Objectives  To evaluate retrospectively the efficacy of the mandibular advancement device (MAD) in Korean patients with obstructive sleep apnea (OSA) in terms of severity and to evaluate prognostic factors deciding the success of MAD application.

Design  Retrospective analysis.

Setting  Academic tertiary referral center.

Patients  Of 142 patients who underwent MAD application for OSA management, 50 (46 men and 4 women; mean [SD] age, 50.2 [9.8] years) were included from March 2005 through August 2007.

Intervention  Full-overnight polysomnography was performed before and at least 3 months after intraoral MAD application in 50 patients. Questionnaires for sleep quality, Epworth sleepiness scale, and cephalometry were also studied.

Main Outcome Measures  Treatment results were evaluated and prognostic factors deciding success of MAD application were assessed.

Results  The mean (SD) apnea-hypopnea index (AHI) decreased significantly (P < .001) from 36.6 (18.9) to 12.3 (11.4). The success rate, defined by an AHI of lower than 20 and a 50% decrease in AHI, were 74% (37 of 50 patients). Even patients who were not categorized into the success group had a decreased AHI. The success rates of patients with mild, moderate, and severe OSA were 43% (3 of 7), 82% (22 of 27), and 75% (12 of 16), respectively, and a higher success rate in patients with severe OSA showed that MAD could be applied even in patients with severe OSA. The duration of apnea and hypopnea, percentage of patients with snoring, and the Pittsburgh Sleep Quality Index were improved significantly after treatment. Epworth sleepiness scale scores and lowest oxygen saturation did not change significantly. An analysis of prognostic factors did not reveal any significant difference between the success and nonsuccess groups.

Conclusions  The application of MAD significantly improved nocturnal respiratory function and sleep quality in patients with OSA, even in patients with severe OSA. In patients with OSA, MAD can be used as a good alternative treatment modality regardless of severity because it is noninvasive, easy to manufacture, and has good treatment results.

  H Chang , H. J Lee , J. H Mo , C. H Lee and J. W. Kim
 

Objective  To evaluate the relationship between findings via osteomeatal unit computed tomography (OMU CT) of the olfactory cleft and olfactory function in patients with chronic rhinosinusitis (CRS).

Design  Retrospective review of medical records.

Setting  Referral center.

Participants  Two hundred ten patients with CRS who underwent OMU CT and olfactory function tests were included in this study.

Main Outcome Measures  All the paranasal sinuses were graded via the Lund-Mackay scoring system. The olfactory cleft was graded on a scale of 0 to 4 according to its opacification. Olfactory function was evaluated by the butanol threshold test (BTT) and the 16-odor identification test (OIT).

Results  The radiologic grade of the olfactory cleft was more significantly correlated with olfactory function than the grades of the paranasal sinuses. In patients without allergy, the BTT and OIT scores were inversely correlated with the CT score of the olfactory cleft. However, in patients with allergy, only the BTT score had a negative correlation with the CT score of the olfactory cleft, whereas the OIT score did not. The OIT score showed a significant negative correlation with the opacification of the olfactory cleft in the mild and moderate CRS group only, whereas the BTT score showed a significant negative correlation in all stages of CRS.

Conclusions  The opacification of the olfactory cleft had a negative correlation with the olfactory function scores in patients with CRS. The olfactory cleft findings on OMU CT may give some clues to the olfactory function in patients with CRS.

  B. S Seo , H. J Lee , J. H Mo , C. H Lee , C. S Rhee and J. W. Kim
 

Objective  To analyze the efficacy of treating postviral olfactory loss with glucocorticoids, Ginkgo biloba, and mometasone furoate nasal spray.

Design  Randomized trial.

Setting  Academic research.

Patients  Seventy-one patients who were diagnosed as having postviral olfactory loss.

Main Outcome Measures  All patients underwent olfactory function tests, including the butanol threshold test (BTT) and the cross-cultural smell identification test (CCSIT), and follow-up tests were performed 4 weeks later. In the interim, 28 patients were treated with prednisolone for 2 weeks (monotherapy), and the other 43 patients were treated with prednisolone for 2 weeks plus G biloba for 4 weeks (combination therapy). All patients used mometasone nasal spray twice daily for 4 weeks.

Results  Scores on the BTT and CCSIT significantly increased after treatment in both groups (P < .001 for both). The mean (SD) BTT score changes were 1.4 (2.2) in the monotherapy group and 2.2 (2.9) in the combination therapy group (P = .22). The mean (SD) CCSIT score changes were 0.9 (1.7) in the monotherapy group and 1.9 (2.7) in the combination therapy group (P = .11). On the BTT, the treatment response (defined as a score increase of ≥3) rates were 32% (9 of 28) in the monotherapy group and 37% (16 of 43) in the combination therapy group (P = .66), and the odds ratio was 1.25 (95% confidence interval, 0.46-3.42). On the CCSIT, the treatment response rates were 14% (4 of 28) in the monotherapy group and 33% (14 of 43) in the combination therapy group (P = .08), and the odds ratio was 2.89 (95% confidence interval, 0.84-9.97).

Conclusions  Olfactory function in patients with postviral olfactory loss was significantly improved by both treatment modalities. Although the treatment response was not statistically different between the monotherapy group and the combination therapy group, the addition of G biloba showed a tendency of greater efficacy in the treatment of postviral olfactory loss.

 
 
 
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