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Articles by J. Anbu Jeba Sunilson
Total Records ( 2 ) for J. Anbu Jeba Sunilson
  J. Anbu Jeba Sunilson , R. Suraj , K. Anandarajagopal , G. Rejitha , M. Vignesh and P. Promwichit
  In this study, petroleum ether, chloroform and methanol extracts of Codium decorticatum showed the presence of amino acids, carbohydrates, saponins, phytosterols, alkaloids and glycosides. The antibacterial activity against Gram-positive bacteria, such as Streptococcus pneumoniae, Staphylococcus aureus and Gram-negative bacteria, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Pseudomonas aeruginosa was carried out using cup-plate method. All the extracts showed good zone of inhibition against S. pneumoniae and K. pneumoniae at the concentrations of 25, 50 and 100 mg mL-1 compared with standard drugs, gentamicin and ampicillin (30 μg mL-1). To standardize the algae, elemental analysis was also carried out on C. decorticatum powder which revealed the presence of various elements. The present findings show the importance of C. decorticatum in producing new compounds having antibacterial activity.
  J. Anbu Jeba Sunilson , G. Rejitha , K. Anandarajagopal , Amitava Das , M. Muthappan and P. Promwichit
  Leaves of Cayratia carnosa have been ethnomedically claimed to possess a wide array of biological activities including anticancer activity. To verify the folklore claim, this study was performed in a Human breast carcinoma cell lines, MCF-7 and MDA-MB-231. Methanol and aqueous extracts of the leaves of C. carnosa showed cytotoxic effect on MCF-7 and MDA-MB-231 cell line, as determined with 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) microculture tetrazolium viability assay. Subcellular alterations were evaluated by using normal inverted microscope. Cells treated with methanol extract showed degeneration of cytoplasmic organelles, profound shrinkage of cells and apoptotic characteristics. The results showed that the methanol extract possesses cytotoxic effect which was greater than aqueous extract when compared to that of the control.
 
 
 
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