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Articles by Iwan Setiawan
Total Records ( 4 ) for Iwan Setiawan
  Asep Anang , Iwan Setiawan , Heni Indrijani and Limai Lan
  Objective: This study evaluated the growth and feed intake of Rambon ducks, a type of local Indonesian ducks. Materials and Methods: This study evaluated growth using 6 models, including the Brody, Gompertz, Logistic, Morgan Mencer Flodine (MMF), Richards and von Bertalanffy models. The feed intake model was estimated using the rational function equation. A total of 80 selectively-bred layer ducks (40 males and 40 females) were reared for 22 weeks. Results: All growth models applied were a good fit for both female and male ducks. The Logistic model with three parameters had the best fit with the highest correlation beween actual and predicted values and lowest standard error of estimation. High correlations also indicated that the rational function model had a good fit and successfully predicted feed intake of the ducks from hatching to 22 weeks. Conclusion: The Brody, Gompertz, Logistic, Morgan Mencer Flodine, Richards and von Bertalanffy models had a good fit and successfully predicted the growth of Rambon ducks from hatching to 22 weeks, however, the Logistic model had the best fit. The rational function model also had a good fit and successfully predicted feed intake of the ducks from hatching to 22 weeks.
  Indrawati Y. Asmara , Tuti Widjastuti , Iwan Setiawan and Abun Hasbuna
  Many studies investigate the use of noni (Morinda citrifolia L.) fruit as natural additive in broiler diets but there is a lack of information on the e ect of Noni in diets on local chickens. The current study aims to determine the effect of Noni fruit extract supplemented with Cu and Zn on production performance of Sentul Chickens. A total of 100 birds of Grey Sentul Chickens aged one day were assigned randomly into 5 treatment groups, each with four replicates and each group treatment contained 5 birds in a completely randomized design. The treatments were basal diet added with different level of Noni fruit extract supplemented by inorganic minerals (CuSO4 and ZnO). The results showed that the addition of Noni fruit extract supplemented with Cu and Zn significantly increased feed intake (in Month II), body weight and body weight gain (in Month III) and carcass weight. However, the treatments reduced the height and width of villi in the intestinal organ of Sentul chickens. The study indicates that increasing Noni fruit extract in diets at a certain level had positive effects on chicken performance.
  Agung Endro Nugroho , Ichwan Ridwan Rais , Iwan Setiawan , Pramita Yuli Pratiwi , Tony Hadibarata , Maulana Tegar and Suwidjiyo Pramono
  Andrographis paniculata (Burm. f.) Nees is a plant that originates from India and grows widely to Southeast which used for several purposes mainly as treatment of diabetes mellitus so the aim of this study was evaluate andrographolide for its pancreatic effect in neonatal streptozotocin (STZ)-induced diabetic rats, a model of type 2 diabetic rats. Diabetic condition was induced with an intraperitoneal injection of 90 mg kg-1 streptozotocin in two-day-old rats. After three months, the neonatal STZ-induced diabetic rats were treated with andrographolide or andrographolide-enriched extract of A. paniculata (AEEAP) for 8 consecutive days. Pancreatic effect was evaluated by estimating mainly the preprandial and postprandial blood glucose levels and other parameters such as morphology of pancreatic islet, beta cells density and morphology and immunohistochemically pancreatic insulin. Andrographolide significantly (p<0.05) decreased the levels of blood glucose and improved diabetic rat islet and beta cells. However, AEEAP exhibited moderate hypoglycaemic effects on the blood glucose levels. Moderate changes in beta cells were observed after AEEAP treatment. They could restore decreasing of pancreatic insulin contents. Based on these results andrographolide and AEEAP exhibited pancreatic actions in neonatal STZ-induced diabetic rats. The activity of andrographolide was more effective than this of AEEAP.
  Iwan Setiawan , Lovita Adriani , Zakiaturrahmi , Hanna Goenawan , Vita Murniati Tarawan and Ronny Lesmana
  Background and Objective: Soy yogurt is fermented soy milk and its nutrient-rich with isoflavones. Soy yogurt decreases blood glucose levels by utilizing the conversion of isoflavones. This study aimed to analyze the effect of soy yogurt on blood glucose level and Glut4 gene expression on rats' soleus muscle. Materials and Methods: Twenty-five rats (eighteen-weeks old) were divided into 5 groups, e.g., the control (P0), positive control (P1, 100% yogurt) and three treatment groups (P2, 50% soy yogurt+50% yogurt; P3, 75% yogurt+25% soy yogurt and P4, 75% soy yogurt+25% yogurt). All treatment groups were treated with different soy yogurt formula and administered for 12 weeks by gavaging. Under anesthetized, rats were sacrificed, then blood samples and soleus muscle were collected and stored at -80°C until use. RNA was extracted from soleus muscle and run for Glut4 mRNA expression using (RT)-PCR. Data were analyzed using one way ANOVA and followed by post hoc test LSD (Least Significant Differences test). Results: There is no difference in rat body weight among groups after 12 weeks of soy yogurt consumption. Blood glucose levels were decreased at least 25% lower level compared to the control baseline by the various formulation of soy yogurt. Interestingly, there is a distinct pattern of Glut4 mRNA expression level in the soleus muscle, P1 increased the expression but not with other formulations decreased the expression (P2, P3 and P4). Conclusion: Taken together, a different formulation of soymilk and cowmilk effectively reduces blood glucose level and modulates Glut4 mRNA expression. In addition, a specific combination of bacteria type for fermenting soy yogurt could be a key to effectiveness for modulating blood glucose levels.
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