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Articles by Ismail Aytekin
Total Records ( 5 ) for Ismail Aytekin
  Nuri Mamak and Ismail Aytekin
  The aim of the present report was to describe the clinical signs, haematological findings and post-mortem lesions in sheep developing fatal complication after enterotoxaemia vaccination in an Awassi sheep flock in Hatay Province. The study included 3 Awassi ewes of 4 years old and 3 lambs from a sheep flock recently vaccinated against enterotoxaemia. Following blood samples collection for routine haematology the live animals were euthanized and subjected to necropsy along with dead animals at the department of pathology. In the histopathological examination, the liver contained multiple, small, randomly distributed foci of necrosis that contained neutrophils. The lungs were affected by mild intra-alveolar and interstitial hemorrhages. There was oedema and haemorrhage around arterioles and venules in the cerebrum. To improve the margin of safety and decrease undesired reactions, pharmaceutical companies provide specific guidelines for the administration of vaccines. However, even when vaccines are administered correctly, there is still the potential for an adverse reaction in a small proportion of the flock. Therefore, further research is obviously needed to discover of developing such an adverse effect.
  Nuri Mamak and Ismail Aytekin
  In this study, it was aimed to present a snake bite and following complications in a dog. A 3 years old male pointer dog, which was brought to the clinic with snake bite complaint, was used in this case. In the anamnesis, it was obtained that the dog was bitten by a snake in the field 2 days ago. In the clinical examination of the dog, two snake bite evidence with hemorrhage spreading from the paw to the whole front leg and ecchymosis were detected. In addition, weakness, reluctant to walk, increase in body temperature, respiratory and pulse rate, abundant salivation and hematuria were the major findings. In the therapy, the bitten area was irrigated with antiseptic solutions and cold application was applied to the region. Antibiotic (Cefazolin sodium) and antihistaminic (Mepyramine maleat) were administered by intravenous fluid therapy (5% Dextrose + 0.9% Sodium Chloride). In addition to therapy, bandage was applied to the swelling leg. On the third day of the treatment, severe necrosis and muscle degeneration were detected. Hence, it was decided to amputate the necrotic leg. Unfortunately, the dog died during the operation. It was thought that without administering first aid medication and antivenin after being snake bitten, mortal complications may occur in such cases.
  Ismail Aytekin , Harun Alp , Nuri Mamak and Savas Aslan
  Study material consisted as 15 experiment and 8 control, totally 23 cattle that possessed by 2 breeders and together housed in Afyonkarahisar province, Suhut district, Kilickaya village; despite vaccine used two times for medicinal purpose displaying no recovery; aged at between 3 and 12 months, diagnosed as dermatofitosis by clinically and microbiological. Being clinical for dermatofitosis the animals in experiment and control groups were examined if there were lesions on the head and derm or not and was categorized as light, bland and acute according to its frequency. The clinical status were examined according to the localization, amplitude and number of lesions. During the study any change was done in condition of animal care, nutrition and shelter. The experiment group was made up 15 cattle; two of them were examined as light, five of them were examined as bland and eight of them were examined as acute and the control group was made up 8 cattle; one of them was examined as light, third of them were examined as bland, fourth of them were examined as acute. Ten percent Enilconazole solution was applied in 4 mg kg-1 dose three days apart as externally to the animals in experiment group. The first application to entire body of the animal and the subsequent 4 applications were done externally in the style of spray to the parts where the dermatofitosis lesions were appeared. The cattle in the control group weren’t applied any therapy. Following the drug administration, in second and fourth weeks a decrease in the keratinized tissues and becoming pilosity were observed in the lesional parts in all experiment group animals. It was seen in the 6th week that keratinized tissues completely decreased, pilosity became dense and the healing was faster. It was determined in the 8th week that lesions recovered completely. It was seen that when any application was made to the control groups animal there were no change in dermatofitosis lesions. As a result, it was of the opinion that owing to easy using, being curative in a short time and being economic of the 10% enilconazole solution was a useful and an alternative medicine for the dermatofitosis therapy in the cattle.
  Ismail Aytekin and Nuri Mamak
  In Afyonkarahisar province, a Holstein cow, which has TR030000075876 ear-number and born on the 27/04/2002 was referred to clinic with complaints of anorexia and apathy. Pain, salivation, tenesmus, bellowing with tongue hanging out, leaning against objects, attempting to bite of objects, occasional postural appearance of kyphosis, hydrophobia and dysphagia were detected in the clinical examination. Rabies was considered in the cow and the obtained pathological samples (head) were sent to the laboratories of Konya Control and Research Institute. Diagnosis of rabies was made by fluorescent antibody technique in the samples. It was thought that the rabies should be taken into account in ruminants showing neurological symptoms besides anorexia and apathy.
  Harun Alp , Ismail Aytekin , Onur Atakisi , Namik Kemal Hatipoglu , Kemal Basarali , Metin Ogun , Sadik Buyukbas , Levent Altintas , Husamettin Ekici and Ayse Alp
  The aim of this study was to investigate the effects of Caffeic Acid Phenethyl Ester (CAPE) and Ellagic Acid (EA) on acitivities of Malondialdehyde (MDA), reduced Glutathione (GSH) and Nitric Oxide (NO) in rat lung, liver and kidney tissues in acute Diazinon (DI) toxicity. Six groups of 6 Sprague Dawley rats were used comprising control, CAPE, EA, DI control, DI+CAPE and DI+EA. Tissue samples were analysed for GSH, MDA and NO levels in lung, liver and kidney tissues. Biochemical parameters were measured colormetrically by spectrophotometer. Control, CAPE and EA groups showed no statistically significant difference whereas DI+medication groups revealed that CAPE and EA increased the level of GSH in liver tissue by blocking the DI effect. NO levels in lung, liver and kidney tissues were significantly increased by DI but CAPE and EA attenuated those levels. In DI+medication groups, MDA levels showed no significant change in kidney and liver tissues but in lung tissues, CAPE and EA reduced the MDA level by blocking the DI effect. It was concluded that CAPE and EA which showed similar effects to each other could be used for protection and support against oxidative stress caused by acute DI intoxication.
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