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Articles by Ismail Alhaji Mairiga
Total Records ( 3 ) for Ismail Alhaji Mairiga
  Mohammed Shaibu Auwal , Sanni Saka , Abdullahi Shuaibu , Ismail Alhaji Mairiga , Kyari Abba Sanda , Amina Ibrahim , Fatima Abba Lawan , Ahmad Bello Thaluvwa and Abdulhamid Baba Njobdi
  The phytochemical properties and hypoglycemic activity of the aqueous and fractionated portions of Acacia nilotica (Thorn mimosa) pod extracts on blood glucose level in wistar albino rats was studied. The result of the phytochemical analysis of the aqueous extract of Acacia nilotica pod revealed that tannins, saponins, flavonoids, carbohydrate and glycosides are present, while anthraquinones, alkaloids, terpene and steroids were absent, the fractionated pod extracts showed moderate carbohydrates, tannins, saponins, cardiac glycosides and flavonoids in ethyl acetate fraction and low amounts in N-butanol fraction. The residue fraction has all the phytochemicals mentioned in the fractionated portions except flavonoids that are absent. There was significant (p<0.05) decrease in blood glucose level in the rats treated with 400-800 mg kg-1 of aqueous extract and 800 mg kg-1 of Ethyl-acetate and N-butanol fractionated 12-18 h post extract administration, respectively.
  Mohammed Shaibu Auwal , Abdulnasir Tijjani , Fatima Abba Lawan , Ismail Alhaji Mairiga , Amina Ibrahim , Abdulhamid Baba Njobdi , Abdullahi Shuaibu , Kyari Abba Sanda , Abubakar Muhammad Wakil and Ahmad Bello Thaluvwa
  The quantitative Phytochemistry and hypoglycaemic properties of crude mesocarp extract of Hyphaene thebaica (doumpalm) on normoglycemic wistar albino rats were investigated. Fresh mesocarp of Hyphaene thebaica was bought in September 2012 from Gamboru market, Borno State, North eastern, Nigeria. One hundred and 50 g of aqueous product were prepared by reflux method from three hundred and 50 g of initial powdered sample. Phytochemical screening for biochemical and elemental contents were conducted. The quantitative phytochemical screening revealed the presence of low level of tannins, steroids and moderate level of saponins, carbohydrates, cardiac glycosides, flavonoids, terpenes and terpinoids. Elemental analysis of the extract revealed the presence of calcium, magnesium, potassium, iron and sodium in moderate concentration, manganese, zinc and silicon is low, whereas the amount of nickel, cobalt, molybdenum, arsenic and lead are negligible. Administration of crude mesocarp extract of Hyphaene thebaica in normoglycemic rats at the dosage of 400, 600 and 800 mg kg-1 for four weeks significantly (p<0.05) reduced blood glucose level of the rats at 3-4 weeks post administration. This finding validates the traditional application of Hyphaene thebaica crude mesocarp extract in the management of Diabetes mellitus in Borno State, Nigeria.
  Mohammed Shaibu Auwal , Sanni Saka , Patrick Azubuike Onyeyili , Ismail Alhaji Mairiga , Abdullahi Shuaibu , Amina Ibrahim , Fatima Abba Lawan , Ahmad Bello Thaluvwa and Abdulhamid Baba Njobdi
  The study to evaluate glycaemic activity of aqueous pod extract of Acacia nilotica in normal and diabetic Wistar albino rats was conducted. Three hundred and fifty grams of the powdered sample were exhaustively extracted with distilled water using reflux method. Phytochemical investigation of the aqueous extract showed that carbohydrate, tannins, saponins, glycosides and flavonoids were present in the extract. The concentrations of Fe, K and Mn in the Acacia nilotica pod extract were within safety limit. However, the concentrations of some other elements such as Mn, Zn, Ca, Na, Cd and Cu were much lower than the acceptable levels. Elements like Pb, As and Mo were absent. There was significant (p<0.05) decrease by 13.19, 13.95, 11.73, 16.40, 28.80 and 25.46%, respectively in blood glucose level of normal rats and 14.12, 32.28, 49.67, 38.97 and 74.61% in diabetic rats treated with 400, 600 and 800 mg kg-1 of aqueous extract at 12 and 18 h post administration. Conclusively it has been deduced from the in vivo study that the extract of this plant can be used in the management of hyperglycemic condition, hence can assist in the management of disease condition such as diabetes.
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