Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species

Jun- Qing Du, Jian Wu, Hua- Jie Zhang, Ya- Hui Zhang, Bei- Ying Qiu, Fang Wu, Yi-Hua Chen, Jing- Ya Li, Fa -Jun Nan, Jian -Ping Ding and Jia Li

The Journal of Biological Chemistry 283 ( 44 ): 30205 - 30215 , 2008