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Articles by Houria Berrebbah
Total Records ( 2 ) for Houria Berrebbah
  Amina Saib , Houria Berrebbah , Mohamed-Reda Djebar and Malika Berredjem
  We performed this work to highlight the in vitro antifungal properties of two amidophosphonates newly synthesized (AP1, AP2). These molecules were synthesized from amino esters and chloroacetyl chloride in two steps using the Michaelis-Arbuzov reaction. We have selected after testing several concentrations 15, 20 and 25 μM for AP1, 10, 25, 40 μM for AP2. The study of the antifungal power by solid medium-diffusion method was performed after microscopic study and purification of fungal isolates from wheat leaves hard, give us the opportunity to identify two fungi: Septoria tritici and Aalternaria tenuis. Results show an antifungal power of two molecules, the growth inhibition-percentage is higher among Aalternaria tenuis. In addition, AP2 molecule appears to have a stronger antifungal activity. Determining the Minimum Inhibitory Concentration (MIC) by the dilution method in liquid medium, shapeless on the effectiveness of our molecules which is to order of 40 μM (AP1) and 25 μM (AP2) for Septoria tritici, 25 μM (AP1) and 15 μM (AP2) for Alternaria tenuis.
  Ouissem Moumeni , Houria Berrebbah , Zoubir Azzouz , Rima Amamra , Hadjer Otmani , Amel Alayat , Sana Benosmane and Mohamed Reda Djebar
  The continuous contamination of the aquatic environments by numerous agricultural and industrial pollutants has triggered the need to identifying new models and bioassays for assessing water pollution and understanding toxic effects of these xenobiotics at different levels. In the present study, investigation was done on physiological changes and antioxidant responses of the freshwater ciliate Paramecium tetraurelia exposed to a selective herbicide; Focus Ultra (a.i., cycloxydim: 100 g L–1). Our results revealed an inhibitory effect on the cell proliferation rate. The growth inhibitory concentration (IC50) was found to be 7.53 mg L–1. Thus, the number and the velocity of generation were decreased when the generation time was extended significantly at the higher concentration of Focus Ultra (12 mg L–1). The normal functioning of the contractile vacuole was also significantly affected at this concentration. Focus Ultra caused evenly a dose dependent stimulation of the phagocytic activity. Furthermore, monitoring biomarkers of oxidative stress showed a significant depletion in glutathione level (GSH) accompanied with a strong increase of glutathione S-transferase (GST) and catalase (CAT) activities reflecting the toxic effects of this herbicide on Paramecium tetraurelia cells.
 
 
 
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