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Articles by Hossein Nazemiyeh
Total Records ( 2 ) for Hossein Nazemiyeh
  Nazli Namazi , Ali Tarighat Esfanjani , Javad Heshmati , Amir Bahrami and Hossein Nazemiyeh
  This study focuses on effects of aerial portions of Urtica dioica (Nettle) on some cardiovascular risk factors in diabetes mellitus. Databases including Pubmed, Science direct, Scopus, Google scholar and IranMedex, were searched for terms: lipid profile, glucose, Insulin Resistance, Oxidative stress, Inflammation, Cardiovascular disease, Blood Pressure, Diabetes and Nettle from 2000 till December 2011. Studies on Nettle root, mixed herbs, unpublished and review articles were excluded. Three human, 18 animal and 7 in vitro or in vitro studies were reviewed. More studies showed positive effects of nettle on decreasing cardiovascular risk factors in diabetes or non-diabetes. Available evidences suggest that Urtica dioica can prevent patients with diabetes from cardiovascular disease with different mechanisms. Because of different dosage, Nettle type and duration of intervention, comparison of studies are difficult. So Further studies need to determine effective dosage of Urtica dioica for decreasing cardiovascular risk factors in patients with diabetes mellitus.
  Seyed Mehdi Razavi , Saber Zahri , Hossein Nazemiyeh , Gholamreza Zarrini , Sariyeh Mohammadi and Mohammad-Amin Abolghassemi-Fakhri
  A known furanocoumarin, 8-geranyloxy psoralen, was isolated from n-hexane extract of Prangos uloptera roots by the TLC method. Its structure was determined by comparison of the spectral data with the literature. Cytotoxic effects of the isolated compound were determined by MTT and Tripan blue assays. The antioxidant and antimicrobial potential of the compound were evaluated by DPPH assay and agar dilution method, respectively. The MTT assay results showed that 8-geranyloxy psoralen reduced cell viability of Hela and Mc-Coy cell lines with IC50 values of 0.792 and 0.835 mM, respectively. Based on the Tripan blue asay, the compound has cytotoxic effects, with an IC50 value of 1.26 mM for Mc-Coy cell line. The compound exhibited weak antioxidant potential, with an RC50 value of 0.262 mg mL-1 and high antimicrobial effects against Staphylococcus epidermidis and Candida kefyr.
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