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Articles by Hossein Hassanpour
Total Records ( 3 ) for Hossein Hassanpour
  Abdolkarim Zamani Moghadam , Habibolla Nazem , Iraj Karimi , Izad Abolhasani Darani and Hossein Hassanpour
  To clarify the effects of Creatine Monohydrate (CrM) supplementation on growth performance and to evaluate histopathological lesions in rats and broiler chickens. Two species of animals, chickens and rats were maintained on standard conditions. Each of species (thirty six rats and thirty six chickens), were separated into three equal groups of twelve animals. The control group receiving no CrM while the experimental groups received CrM added to the water supply to achieve a dose of 0.25 and 0.5 g kg-1 day-1. The body weight and feed intake were measured and feed conversion rate was calculated. All animals were dissected after 15 days; Portions of liver, kidney, skeletal muscle, were separated and prepared for histopathological sections. There were not any significant variations in body weight gain and feed conversion rate between control and creatine-supplemented groups in rats. There were not also any change in feed conversion rate in chickens but body weight gain significantly (p<0.05) increased at day 15 of rearing in creatine-supplemented group (0.5 g kg-1 day-1) compared to its control. Histopathological changes were not significant in two species. This study showed that creatine do not have any pathological effect on liver, kidney and muscle of rats and chickens and can improve body weight gain in rearing chickens.
  Hossein Hassanpour , Pejman Mirshokrai , Abolfazl Shirazi and Atefe Aminian
  The aim of this study is to investigate the effects of NO on sperm motility of ram. After incubation of normozoospermic samples for 160 minutes in the presence of L-arginine (NOS substrate ), SNP (NO donor), L-NAME (non-selective nitric oxide inhibitor) and packed erythrocytes (NO scavenger), sperm motility assessed in four grades (A, B, C, D). In this study, L-arginine and SNP non-significantly increased progressive motility at low concentration and significantly decreased progressive motility at high concentration. L-NAME and packed erythrocytes dose- dependently decreased progressive sperm motility. It is concluded that sperm motility of ram physiologically depend on nitric oxide action although excess generation of nitric oxide by sperm or exogenous NO could not increase sperm motility and it seems that excess NO provides toxic condition to decrease sperm motility.
  To clarify the effect of acetic acid on the electrocardiographic parameters of pulmonary hypertensive broilers, chicks were reared at high altitude and treated with acetic acid (0.4 and 0.9 g/L) for 45 days. The right ventricle-to-total ventricle ratio was noted as an index of pulmonary hypertension that was significantly (P < 0.05) decreased in the treated groups. S amplitudes were significantly decreased only at 36 days (leads II and III) and 45 days (lead aVF) in many treated groups. There were significant (P < 0.05) reductions of T amplitudes at 28 days (leads aVR and aVL) and 36 days (lead aVL), and significant elevations of QRS (leads II, III, and aVF) and QT intervals (leads II, aVR, aVL, and aVF) at different ages of many treated groups. R amplitudes were significant (P < 0.05) at 28 days (leads aVL and aVF, at both doses of acetic acid), 36 days (leads aVR and aVL, at 0.4 g/L of acetic acid), and 45 days (lead aVR, at both doses of acetic acid). The RR interval also significantly increased at 28 days (leads aVR and aVL) and 45 days (lead aVL). It was concluded that acetic acid modulates induction of ventricular hypertrophy, dilation, and arrhythmia. These effects are detectable in many electrocardiographic parameters.
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