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Articles by Hiroko H. Dodge
Total Records ( 3 ) for Hiroko H. Dodge
  Hiroko H. Dodge , Chung-Chou H. Chang , Ilyas M. Kamboh and Mary Ganguli
  Background Although Alzheimer‘s disease (AD) is a neurodegenerative disorder, there is growing interest in the influence of vascular factors on its incidence. Methods In a population-based longitudinal epidemiological study, we fit Cox proportional hazard models to examine the risk of incident dementia and AD associated with self-reported vascular disease. The population-attributable risk percent (percent of the incidence of dementia and AD in the population that would be eliminated if vascular disease was eliminated) was calculated using the adjusted hazard ratios (HR). Results Of 822 eligible participants, 94 individuals developed incident dementia, with 79 having AD (probable/possible AD) during the follow-up period of on average 8 years. Stroke/transient ischemic attack history was associated with incident dementia (HR = 2.6) as well as AD (HR = 2.4) among non-apolipoprotein E ɛ4 carriers. Conclusions At the community level, the risk of dementia could be potentially reduced by 10.8% by eliminating overt cerebrovascular disease, and the risk of AD by 9.1% for non-apolipoprotein E ɛ4 carriers.
  Katherine V. Wild , Nora C. Mattek , Shoshana A. Maxwell , Hiroko H. Dodge , Holly B. Jimison and Jeffrey A. Kaye
  Background This study examines differences in computer-related self-efficacy and anxiety in subgroups of older adults, and changes in those measures after exposure to a systematic training program and subsequent computer use. Methods Participants were volunteers in the Intelligent Systems for Assessment of Aging Changes study (ISAAC) carried out by the Oregon Center for Aging and Technology. Participants were administered two questionnaires before training and again 1 year later, which were related to computer self-efficacy and anxiety. Continuous recording of computer use was also assessed for a subset of participants. Results Baseline comparisons by sex, age, education, living arrangement, and computer proficiency, but not cognitive status, yielded significant differences in confidence and anxiety related to specific aspects of computer use. At 1-year follow-up, participants reported less anxiety and greater confidence. However, the benefits of training and exposure varied by group and task. Comparisons based on cognitive status showed that the cognitively intact participants benefited more from training and/or experience with computers than did participants with mild cognitive impairment (MCI), who after 1 year continued to report less confidence and more anxiety regarding certain aspects of computer use. Conclusion After 1 year of consistent computer use, cognitively intact participants in this study reported reduced levels of anxiety and increased self-confidence in their ability to perform specific computer tasks. Participants with MCI at baseline were less likely to demonstrate increased efficacy or confidence than their cognitively intact counterparts.
  Deniz Erten- Lyons , Lena O. Sherbakov , Andrea M. Piccinin , Scott M. Hofer , Hiroko H. Dodge , Joseph F. Quinn , Randy L. Woltjer , Patricia L. Kramer and Jeffrey A. Kaye
  One of the recommendations of the 2010 Leon Thal Symposium, organized to develop strategies to prevent Alzheimer‘s disease, was to build a global database of longitudinal aging studies. Although several databases of longitudinal aging studies exist, none of these are comprehensive or complete. In this article, we review selected databases of longitudinal aging studies. We also make recommendations on future steps to create a comprehensive database. Additionally, we discuss issues related to data harmonization.
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