Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by Hesham Mottawie
Total Records ( 4 ) for Hesham Mottawie
  Khaled Al-Menabbawy , Amr EL-Khashabb , Mohamad EL-Matarawy , Suzette Hela and Hesham Mottawie
  This study was done on 25 infants with congenital cataract aging 3-18 months and their parents. Another group of 14 infants of same age with no ophthalmic and/or congenital diseases were included as control group with their parents. All cases and their parents were examined clinically and ophthalmologically. Levels of galactose, serum sodium and potassium were determined. A significant elevation in blood galactose, in infants with congenital cataract as compared with control group, while no significant changes in blood galactose levels of their parents as compared with parents of control group. Significant elevation of serum sodium in infants with congenital cataract as compared with control group, while no significant change in serum sodium levels of their parents as compared with parents of control group. Significant decrease of serum potassium in infants with congenital cataract as compared with control group, while no significant change in serum potassium levels of their parents as compared with parents of control group. Early valuable genetic counseling, with estimation of galactose, sodium and potassium are recommended. Infants with congenital cataract had different etiological causes, so not all cases need restriction of milk and milk products. Parental estimation of galactose, sodium and potassium had no value.
  Khaled Al -Menabbawy , Asaad El-Gerzawy , Afaf Ezzat and Hesham Mottawie
  Twenty two cases diagnosed as Attention Deficit Hyperactivity Disorder (ADHD), aged 6-10 years, chosen to study the correlation between developmental, behavioral and genetic factors in relation to some biochemical parameters. Another group of 22 healthy normal children of the same matched age and sexes were collected as control group. All cases and control children were subjected to full clinical and neurological history and examination, anthropometric measurements and behavioral assessment. Levels of folic acid, vitamin B12 and T3, T4 were estimated, for both cases and controls. Cytogenetic examination of peripheral blood lymphocytes were done for cases only. Chromosomal abnormalities were detected in 6 cases out of 22 cases. There was a significant decrease in the weight and BMI, as compared with controls, these decrease was highly significant among those with chromosomal abnormalities. Regarding the behavioral assessment, a significant decrease in three of the four components of Vineland Adaptive behavior scale: (communication, daily living skills and socialization), as compared with controls, this decrease in the three components was highly significant among those with chromosomal abnormalities. A non significant increase in the score of the motor skills, as compared with controls, while significant increase in it`s score was found among those with chromosomal abnormalities. Biochemical studies showed no significant decrease in T3 and T4 levels as compared with controls, while levels of Folic acid and Vitamin B12 showed significant decrease as compared with controls, this decrease in their levels showed highly significant decrease among those with chromosomal abnormalities. We concluded that this study is the first study in our knowledge examining the correlation between developmental, behavioral and genetic factors among children with ADHD in the same subject group. ADHD is multifactorial and is associated with a remarkable increase in chromosomal abnormalities, which affect behavior and anthropometric measurements.
  Amany Zayed , Hager Amer , Hala Nasar , Atef Ibrahiem and Hesham Mottawie
  Sixty cases were included in this study, divided into 2 groups; Group I (Control) (n = 20) and Group II (RA) (n = 40). Estimation of VEGF levels in serum (VEGFBL) and in synovial fluid aspirates of Knee joint in 11 RA patients (VEGFSF) using ELISA, in addition to different acute phase reactants and indices of disease activity. Plain x-ray of both hands to detect juxta-articular osteopenia and erosions. Serum VEGF showed a highly significant difference between Group I (Control) (165.4±46 pg mL-1) and Group II (RA) (886.3±267.8 pg mL-1) (p = 0.000). Serum CRP showed a highly significant difference between Group I (Control) and Group II (RA) (p = 0.000). Serum VEGF showed significant correlation with VEGF in Synovial Fluid (p = 0.012), Articular Index (AI) (p = 0.04), ESR (p = 0.01), Alkaline Phosphatase (ALKPASE) (p = 0.04) and CRP (p = 0.00, highly significant correlation). VEGF levels in synovial fluids (88.7±17.3 pg mL-1) showed a significant correlation with VEGF in serum (VEGFBL) (p = 0.012) of the same RA patients, WBCs (p = 0.02) and CRP (p = 0.00, highly significant correlation). Serum VEGF is higher in RA patients than in controls. VEGF appears to play an active part in joint inflammation in early RA, however, in long-standing RA elevated VEGF serum levels may be an independent mark.
  Khaled AL-Menabbawy , Mona Sallam , Safaa Taha , Hesham Mottawie and Atef Ibrahiem
  In order to determine the clinical conditions and effect of obesity and sedentary life style among adolescents on the systemic oxidative stress, 58 obese young adolescents of both sexes, aged 11-14 years were collected for the study. Another group of 24 healthy normal non obese children of the same matched age and sexes were collected as control group. All cases and controls were exposed to full clinical history and examination, including weight, height and calculation of body mass index. Levels of free and esterified F2-isoprostanes in plasma, concentrations of vitamin C and vitamin E, were measured and levels of erythrocyte superoxide dismutase activity (SOD) as well as erythrocyte catalase activity were estimated. Total cholesterol and triglycerides levels were determined enzymatically as well as HDL and LDL cholesterol levels. Sedentary lifestyle, frequent soft drinks ingestion as well as fast food ingestion represented a common habit, with smoking among this age group as compared with control group. with significant increase in weight and BMI as compared with controls. A significant high levels of free and esterified F2- isoprostanes, total cholesterol levels, HDL cholesterol and LDL cholesterol were detected among obese adolescents as compared with control group. While significant low levels of vitamin C, vitamin E, SOD and catalase enzymes were detected among obese adolescents as compared with control group. We concluded that obesity with sedentary lifestyle are highly associated with systemic oxidative stress, which is reflected on their health and school performance.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility