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Articles by Hengyong Xu
Total Records ( 2 ) for Hengyong Xu
  Hengyong Xu , Yan Wang and Jiwen Wang
  Fat is the main composition of the body, it not only has an important role to maintain the animal’s physiological function but also its precipitation and sedimentary parts have became the key factor to influence the carcass and meat quality. As two members of the family of the fatty acid transport proteins, FATP1 and FATP4 involved in the transport of long chain fatty acids across the plasma membrane and the metabolism of fatty acids. They are the key genes which have an influence on fat content and maintain skin phospholipids metabolism. So, in this study, the characteristic of structure, function and variation of the gene FATP1 and FATP4 have been summarized. Researchers hope this content can provide certain reference for the researchers in the future.
  Xun Wang , Hengmin Cui , Haifeng Liu , Ling Zhao , Xi Peng , Hengyong Xu , Yan Wang , Yuhao Wang , Ling Niang and Qian Rong
  To study the effect of the crude polysaccharides from Poria cocos (PCCP) on mRNA expression of adipogenic factors during 3T3-L1 preadipocyte differentiation. 3T3-L1 preadipocytes were induced to differentiate with MDI (3-isobutyl-1-Methylxanthine, Dexamethasone and Insulin) induction media contained PCCP (50 μg mL-1) and cultured for 8 days. The extent of the differentiation was assessed by Nile Red staining and GPDH activity. In addition, researchers used real-time quantitative PCR to analyzed the expression of genes related to adipocyte differentiation. The results showed that treatment of differentiating 3T3-L1 preadipocytes with PCCP (50 μg mL-1) resulted in an increase in the expression of the adipocyte genes such as Fatty Acid System Synthase (FAS), adipocyte fatty acid binding Protein (aP2), insulin-responsive Glucose Transporter (GLUT4) and transcriptional factor genes such as CCAAT/Enhancer Binding Protein α (C/EBPα), peoxisome Proliferator-Activated Receptor gamma (PPARγ) and Sterol Regulatory Element-Binding Protein 1c (SREBP-1c) to some degree. Overall, the data suggested that there was the tendency of increasing the expression of genes related to adipocyte differentiation in PCCP treated cells.
 
 
 
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