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Articles by Handan Aydin
Total Records ( 2 ) for Handan Aydin
  Handan Aydin , Mehmet Can Gunduz and Hasret Demircan Yardibi
  In this study, the effects of beta receptor blocker (carazolol) on the main detoxifying enzymes, Superoxide Dismutase (SOD) and Catalase (CAT) in sheeps were investigated. Two group (n = 6) were design. 1 mL ewe-1 of serum physiologic were administered i.m. to the control group (Group 1) and 0.5 mg ewe-1 of carazolol were injected i.m. to the treatment group (group 2). After treatment the blood samples were collected at 24, 48 and 72 h. No differences were observed in antioxidant enzyme values in sheep plasma. Also, no effect was seen on oxidative stress marker. Here, we show that carazolol may be alternatively used as a β-blocker agent in sheeps.
  Handan Aydin , Alper Baran , Abit Aktas , Kamber Demir , Elif Sahin , Abdullah Kayar , Serhat Pabuccuoglu and Suzan Daglioglu
  Two, 4-Dichlorophenol (2, 4-DCP), an environmental pollutant has been in agriculture and synthetic chemical industry. The aim of present study was to analyse the testicular toxicity of 2, 4-DCP, which caused biochemical, spermatological and histological changes in male mice and to evaluate the possible ameliorative effect of soybean extract and L-Tryptophan (L-TRP). Soybean extract (25 mg/kg bw/day) and L-TRP (150 mg kg-2 bw/day) were given by intraperitoneal (ip) route for 14 days. 2, 4-DCP was administered to male mice with drinking water at dose of 1000 ppm for 14 days. Biochemical parameters in serum ((glucose, creatinine, Blood Urea Nitrogen (BUN), Aspartate Transaminase (AST), Alanine Transaminase (ALT), Lactate Dehydrogenase (LDH)), spermatological and histological changes were investigated at the end of the 14 days comparatively with control group. We conclude that soy extract and L-tryptophan alleviate 2, 4-DCP testicular toxicity.
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