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Articles by Hajer Abaza
Total Records ( 1 ) for Hajer Abaza
  Sarra Khlifi , Houda Ben Jemaa , Halima Ben Hmad , Hajer Abaza , Inchirah Karmous , Abdelmajid Abid , Anis Benzarti , Jalila Elati and Abdallah Aouidet
  Fenugreek (Trigonella foenum-graecum) seeds have been known as a traditional plant treatment for diabetes. The aims of this study were to determine the antioxidant activity of fenugreek seeds and to evaluate the antidiabetic and antihyperlipidemic effect of fenugreek seeds intake on diabetic patients. Sixty newly diagnosed diabetic patients were recruited for this study and have received two doses of fenugreek seeds (2.5 and 5 g) for 4 weeks. Phytochemicals analysis and antioxidant activity of Trigonella foenum-graecum seeds methanolic extract were also studied. The chemical analysis of fenugreek seeds exhibited a high level in total polyphenols (9.5 GAE g/g VM) and flavonoids (3.7 mg RE/g VM). Fenugreek seeds exertan important DPPH scavenging ability in terms of Trolox Equivalents (TE) with 1.03±0.008 mg TE/g VM and also exhibited a high antioxidant potential according to ABTS test. In Tunisian type 2 diabetic patients, the administration of fenugreek seeds (2.5 and 5 g) for 4 weeks improved blood glucose level in dose-dependent. Total cholesterol and triglycerides rate were significantly decreased by the dose of 5 g Trigonella foenum-graecum seeds. Moreover, daily oral intake of our treatment by diabetic subjects reduced significantly serum α-amylase activity. The present findings indicate that fenugreek seeds with abundant flavonoids and total polyphenols content may be a good adjuvant for the treatment of diabetes.
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