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Articles by H.B. Osadolor
Total Records ( 2 ) for H.B. Osadolor
  H.B. Osadolor , E.A.C. Nwanze and O.G. Anoliefo
  Kutchalli Drilling Waste-Pit Materials (KWPM) in Nigerian National Petroleum Corporation (NNPC) exploration sites in Borno state of Nigeria were investigated for system toxicity to inhabitants (man, animals and plants) via food chain. After the determination of the physiochemical properties of the KWPM, photochemistry and seedling evaluation were assessed for the produce (groundnuts) grown in the different Kutchali experimental waste-pit materials soils. The produce in combination with growers mash were used to compound the feed regime and administered orally to New Zealand inbred rabbits (5/group) at 100 g feed/day for 14 weeks. Electrolytes and some kidney biomarkers of the laboratory rabbit models fed on groundnuts grown in the KWPM were determined to evaluate the functional status of the kidneys The biochemical parameters to assess the kidney (Urea, Creatinine and Electrolytes) of the laboratory rabbits revealed significant difference between those fed on groundnuts harvested from KWPM and those of normal soil, respectively (GP 1: Urea 28± 4.1, Creat. 0.7±0.2, GP 5, Urea 45±3.0, Creat. 2.1±0 and GP 7: Urea 51±3.5, Creat. 1.8±0.3) p<0.05. The parameters used in this study were analysed by atomic emission spectrophotometry and SMAC autoanalyzer supplied Techniconinstruments, NY 10591. All the parameters used to assess the kidney varied from the control at different weeks of the experimental trials (GP 5 and 7 varied significantly from control). The inhabitants of Kutchalli where this research was conducted are predominantly farmers, fishers and cattle rearers, so, if proper waste management is not embarked upon, they including the vegetation may soon face extinction.
  H.B. Osadolor , I.I. Ariyo , M.A. Emokpae and K.C. Anukam
  This study was carried out to evaluate the hypoglycemic effect of unripe pulp of Carica papaya on streptozotocin induced diabetic albino rats. Thirty male albino rats were used for this study. The animals were examined by a veterinary doctor and allowed to acclimatize for two weeks. The animals were divided into three groups of 10-animals each. Group 1 (test), group 2 (induced control) and group 3 (normal control). Group 1 was fed with unripe pulp of pawpaw while group 2 and 3 were fed with a commercial feed (grower marsh). Samples from five animals were collected from each group after three weeks, another five samples were collected from each groups after five weeks. Plasma glucose level was determined by glucose oxidase method. The mean and standard deviation of the values obtained from group 1 (test) at week 3 and 5 were 56.0±6.0 and 35.8±6.9. The mean and standard deviation of the values obtained for group two (induced control) at week 3 and 5 were 155.0±8.0 and 159.0±4.3 and the mean and standard deviation of the values obtained for group 3 (normal control) were 113.2±3.4 and 112.0±3.2. All the results were statistically significant (p<0.05) at week 3 and 5 when compared with controls. This study revealed the hypoglycaemic effects of the pulp of unripe Carica papaya. Therefore, there is urgent need to conduct double-blind, randomized placebo-controlled human trial to decipher whether the same hypoglycemic effects could be obtained in human subjects.
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