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Articles by H Takiuchi
Total Records ( 2 ) for H Takiuchi
  K Shitara , T Yokota , D Takahari , T Shibata , T Ura , Y Komatsu , S Yuki , M Yoshida , H Takiuchi , S Utsunomiya , Y Yatabe and K. Muro
 

Standard weekly cetuximab and irinotecan is an effective regimen in heavily pre-treated patients with metastatic colorectal cancer. The aim of this study is to prospectively evaluate the efficacy of combination chemotherapy with biweekly cetuximab and irinotecan in patients with pre-treated metastatic colorectal cancer harboring wild-type KRAS. A total of 30 patients will be enrolled at four medical institutions. The primary endpoint is response rate. The secondary endpoints include adverse events, progression-free survival and overall survival. The pharmacokinetics of cetuximab will also be evaluated in five patients.

 
 
 
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