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Articles by Gulsen Gunes
Total Records ( 1 ) for Gulsen Gunes
  Fatma Kaynak Onurdag , Tuncer Degim , Zelihagul De im , Ismail Kutlu , Ozgur Kaynar , Gulsen Gunes and Ufuk Abbasoglu
  Brucellosis is an important zoonotic disease and the prevention is made by vaccination of animals. For ewes Brucella melitensis REV-1 live attenuated vaccine is widely used but because of some risks such as being infected during the vaccination, re-infection of animals, a new vaccine with less side effect is need to be improved. In this study it was aimed to determine a strong humoral immune response by encapsulating the Brucella outer membrane antigens with the optimum liposome formulation and the statistical analyses showed that the Brucella outer membrane extract encapsulated with liposome can evoke humoral immune response better than live attenuated B. melitensis REV-1 vaccine in mice.
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