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Articles by Gilles Figueredo
Total Records ( 2 ) for Gilles Figueredo
  A. Zeraib , M. Ramdani , T. Lograda , P. Chalard and Gilles Figueredo
  The essential oils of the aerial parts of two populations of Moricandia arvensis in the Setif region (Algeria) were analyzed by gas chromatography and mass spectrometry (GC-MS). Thirty compounds were identified from the oils of M. arvensis, representing 80.8% of the total essential oil of southern population and 19 compounds of the population north of Setif, representing 93% of total oil. The analysis showed that the essential oils are rich in fatty acid (34.1-22.1%). The major constituent are palmitic acid (13.2-12.9%) and the phytol (7.9-10.5%). The Setif population is characterized by 3-butenylisothiocyanate and Octadecanoic acid, 2-hydroxy-1,3-p. The effects of these oils on the growth of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and Staphylococcus aureus (ATCC 25923) were investigated by the diffusion method. The oils showed no significant antibacterial activity.
  Bagora Bayala , Christelle Nadembega , Samson Guenné , Julio Buñay , Théodora Mahoukèdè Zohoncon, , Florencia Wendkuuni Djigma , Albert Yonli , Silvère Baron , Gilles Figueredo , Jean-Marc A. Lobaccaro and Jacques Simpore
  Background and Objective: Hyptis suaveolens is an aromatic plant used in traditional medicine in Burkina Faso for management of various diseases including wounds and inflammatory diseases. Thus, the objective of this work was to characterize the chemical composition, antioxidant and cytotoxic activity of Essential Oil (EO) of H. suaveolens from Burkina Faso on cultured cancer cells. Materials and Methods: The chemical composition of EO was determined by GC/FID and GC/MS analysis and the antioxidant activity was evaluated through inhibition of DPPH radicals and ABTS + radical cations. The cytotoxic activity in prostate cancer cells (LNCaP) and cervical cancer cells (HeLa) of EO was evaluated by MTT assay and effect on cells cycle by flow cytometry analysis. Results: A total of 58 compounds were identified in the EO of H. suaveolens of which the major compounds identified are Sabinene 14.03%, β-Pinene 5.92%, Limonene 4.40%, Eucalyptol 12.78%, Trans-Oxide of Linalol 5.43%, β-Caryophyllene 11.27%, Germacrene-D 3.04% and Bicyclogermacrene 8.08%. The EO of H. suaveolens showed antioxidant activity and concentration dependent antiproliferative activities with G0/G1 arrest on LNCaP and HeLa cells. Conclusions: This work help to justify some uses of H. suaveolens in traditional medicine in Burkina Faso and also, presents a promising new application for the essential oil of H. suaveolens in prostate and cervical cancer research.
 
 
 
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