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Articles by Gholamreza Amin
Total Records ( 2 ) for Gholamreza Amin
  M.H. Salehi Sourmaghi , Gholamreza Amin , Nasrin Samadi , Farnaz Hemmati and Parisa Sarkhail
  The aerial parts of Salvia spinosa L. (Labiatae) afford an essential oil on hydro distillation was analyzed by gas chromatography-mass spectroscopy (GC/MS) using direct injection. Out of 19 peaks (representing 99.99% of the oil), 18 Components were identified representing 98.59% of the total oil Composition. The major Components were 1,8-cineol (32.87%), (Z)-β-ocimene (20.03%), Germacrene d (10.66%), 2-Butyl thiophene (9.83%), Trans caryophyllene (5.01%) and 3- Butyl thiophene (3.49%). The oil was also screened for its antimicrobial activity against four bacteria (Staphylococcus aureus, Basillus subtilis, Psedomonas aeruginosa and Escherichia coli) and two fungal strains (Candida albicans and Aspergilus niger) using Disc diffusion method and also Minimum Inhibitory Concentration (MIC) values of each active oil concentration were determined. The results showed a significant activity against Staphylococcus aureus, pseudomonas aeruginosa and Basillus Subtilis.
  Naghmeh Hajarolasvadi , Mohammad J. Zamani, , Parisa Sarkhail , Reza Khorasani , Masoomeh Mohajer , Gholamreza Amin , Abbas Shafiee , Mohammad Sharifzadeh and Mohammad Abdollahi
  The objective of the present study was to evaluate the anti-inflammatory and analgesic activities of the crude and fractioned extracts (ether, ethyl acetate, n-butanol and water) of Phlomis anisodonta (Lamiaceae) in the models of carrageenan-induced paw edema and acetic acid-induced writhing in mice. Dried powdered material from the aerial parts of Phlomis anisodonta was extracted with methanol (80%) twice. The methanol extract was separated into four fractions: after drying the methanol extract, the solid residue was dissolved in water and the water-soluble portion was successively partitioned to produce the above-mentioned fractions. The total extract, ether fraction and ethyl acetate fractions significantly reduced the number of writhings compared to the control group. Water and n-butanol fractions showed no analgesic activity. Neither the total extract nor four fractions were more effective than indomethacin in acetic acid-induced test. In carrageenan-induced inflammation test, only water and ethyl acetate fractions showed antiinflammatory activity compared to the control group. The total extract, n-butanol and ether fractions showed no antiinflammatory activity. Neither the total extract nor four fractions were more effective than indomethacin. Different types of glycosides found in the genus Phlomis could be responsible for observed effects. Variations in antiinflammatory and analgesic effects of different fractions of this plant might be attributed to the fact that different fractions of P. anisodonta contain active compounds in variable ratios and activities. A comprehensive analysis for determination and quantification of these compounds is required).
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