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Articles by G.V. Rajamanickam
Total Records ( 2 ) for G.V. Rajamanickam
  K.S. Vidyalakshmi , A.I. Charles Dorni , Hannah R. Vasanthi , G.V. Rajamanickam and D. Sukumar
  The flowers of Mussaenda glabra occurring in white and pink have been evaluated for their anti oxidant property. The white (MGW) and the pink (MGP) varieties showed considerable NO scavenging activity. The IC50 values were found to be 92.79 and 122.45 μg mL-1, respectively. MGW inhibited lipid peroxidation to a greater extent when compared to MGP. MGW showed 50% inhibition at the concentration of 112.4 μg mL-1 while MGP at 53.42 μg mL-1. The reducing power was found in a dose dependent manner. The pink variety showed greater reducing power when compared to white variety. Both the extracts showed hydroxyl radical and ABTS radical scavenging property. The total phenolic content was 17.5 and 8.3 mg g-1 in MGP and MGW, respectively. The HPTLC fingerprinting showed peaks due to flavonoids. The results show that both are having considerable anti oxidant property. The abundance of this flower throughout the year can be used for evaluating its medicinal value.
  U. Subasini , G.V. Rajamanickam , G.P. Dubey , P.C. Prabu , C. Savariraj Sahayam , M. Mohammed Shabi , K. Gayathri and Aruna Agrawal
  Herbal drugs are considered to be the best alternative for many diseases. Even incurable diseases like cancer, HIV, etc., are moving towards the traditional herbal drugs. The treatment using herbal drugs is gaining momentum to the vital organs like liver, kidney and heart. In such movement, the finding of the presence of effectiveness of hepatoprotective factor from any plant is felt a contributory one. Terminalia arjuna a plant commonly observed in the south India is found to have a property of hepatoprotectiveness. In order to appreciate the hepatoprotective activity of the Terminalia arjuna, hydroalcoholic extract of the same is used here on Albino Wistar mice. The general behaviour of the animals has been studied in comparison to control group with the Terminalia arjuna extract treated animals. A gross pathology and histopathology have also been studied. The results obtained from the study of GOT, GPT and ALP clearly direct the hepatoprotective effectiveness of hydroalcoholic extract of Terminalia arjuna.
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