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Articles by G.P. Senthilkumar
Total Records ( 2 ) for G.P. Senthilkumar
  G.P. Senthilkumar and S. Subramanian
  Impairment of mitochondrial function is intrinsically related with diabetes. Treatment strategies that focus on enhancing mitochondrial function are the important options for diabetes management. The present study was aimed to evaluate the protective effect of Terminalia chebula (T. chebula) fruits on mitochondrial damage in STZ-induced diabetic rats. Oral administration of ethanolic extract of the fruits (200 mg kg-1 body weight day-1) for 30 days significantly increased the activities of mitochondrial enzymes in diabetic rats. Transmission Electron Microscopic (TEM) observations also provided an additional strength to the prophylactic activity of fruit extract. Thus it may be concluded that the presence of biologically active ingredients in the fruit extract of T. chebula potentiate its anti-diabetic properties by regulating the mitochondrial enzymes.
  S. Subramanian , D. Sathish Kumar , P. Arulselvan and G.P. Senthilkumar
  Aloe vera leaf gel is widely used as a traditional folk medicine for the treatment of different infectious diseases. In vitro antimicrobial properties of ethanolic extract of Aloe vera leaf gel were investigated against various common pathogenic bacteria and fungi. The well and disc-diffusion method showed significant zone of inhibition against all the pathogens studied and the results are comparable to the conventional antibiotics. These results support the ethanomedicinal use of Aloe vera for the treatment of various ailments.
 
 
 
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