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Articles by G. Wang
Total Records ( 4 ) for G. Wang
  L He , H Zeng , F Li , J Feng , S Liu , J Liu , J Yu , J Mao , T Hong , A. F Chen , X Wang and G. Wang

Hyperhomocysteinemia (HHcy) has been associated with impaired vascular endothelial function. Our previous study demonstrated significantly higher secretion of the chemokine monocyte chemoattractant protein-1 from monocytes in response to lipopolysaccharide in patients with HHcy. In the present study, we investigated whether coronary endothelial function was damaged in patients with chronic HHcy (plasma level of homocysteine >15 µmol/l) and, if so, whether this impaired endothelial function is induced by the uncoupling of endothelial nitric oxide synthase (eNOS). When tetrahydrobiopterin levels are inadequate, eNOS is no longer coupled to l-arginine oxidation, which results in reactive oxygen species rather than nitric oxide production, thereby inducing vascular endothelial dysfunction. The 71 participants were divided into two groups, control (n = 50) and HHcy (n = 21). Quantification of coronary flow velocity reserve (CFVR) was after rest and after adenosine administration done by noninvasive Doppler echocardiography. Plasma levels of nitric oxide and tetrahydrobiopterin were significantly lower in patients with HHcy than in controls (99.54 ± 32.23 vs. 119.50 ± 37.68 µmol/l and 1.43 ± 0.46 vs. 1.73 ± 0.56 pmol/ml, all P < 0.05). Furthermore, CFVR was significantly lower in the HHcy than the control group (2.76 ± 0.49 vs. 3.09 ± 0.52, P < 0.05). In addition, plasma level of homocysteine was negatively correlated with CFVR. Chronic HHcy may contribute to coronary artery disease by inducing dysfunction of the coronary artery endothelium. The uncoupling of eNOS induced by HHcy in patients with chronic HHcy may explain this adverse effect in part.

  W. Li , G. Wang , X. Wang and S. Li
  The scheduling algorithm for optimistic replication is important, because it has an extreme effect on replication performance. However, most of the scheduling algorithms are designed for a conventional hard disk device with mechanical disk arms. It may be inefficient when the flash memory which possesses both a higher read/write performance and random access rate is equipped. This study proposed a new flash memory-based scheduling algorithm for optimistic replication: FBSA. It parallelized the write requests on the slave node according to the semantic dependency, thus, full drove the flash memory and improved replication performance. The FBSA was fully implemented under a popular open-source DBMS-MySQL and was proved to show dramatic performance improvement compared with the original scheduling algorithm based on the same hardware and software configurations.
  G. Wang , X.P. Gao and P.W. Shen

Cubic spinel Co2SnO4 nanocrystals are successfully synthesized via a simple hydrothermal reaction in alkaline solution. The effect of alkaline concentration, hydrothermal temperature, and hydrothermal time on the structure and morphology of the resultant products were investigated based on X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It is demonstrated that pure Co2SnO4 nanocrystals with good crystallinity can be obtained in NaOH solution (2.0 M) at 240 °C for 48 h. The galvanostatic charge/discharge and cyclic voltammetry were conducted to measure the electrochemical performance of the Co2SnO4 nanocrystals. It is shown that Co2SnO4 nanocrystals exhibit good electrochemical activity with high reversible capacity (charge capacity) of 1088.8 mAh g-1 and good capacity retention as anode materials for Li-ion batteries, much better than that of bulk Co2SnO4 prepared by high temperature solid-state reaction.

  J. Lia , G. Wang , T. Zhu , L. Sun , M. Xu and R. Rong

Background: Traditional open donor nephrectomy (ODN) is associated with good outcomes and excellent allograft function; nevertheless, it causes too much injury to the donor. Hand-assisted laparoscopic donor nephrectomy (HLDN) may accomplish these goals with less damage. We compared the outcomes of the hand-assisted with the traditional open approach. We also investigated whether the availability of the HLDN approach affected a donor`s decision and why he or she selected HLDN versus ODN.

Materials and Methods: We retrospectively analyzed donor and allograft outcomes for the first 65 patients undergoing HLDN at our institution compared with those of 32 patients undergoing traditional ODN. Patient data were obtained from medical record reviews and telephone interviews.

Results: HLDN and ODN were successfully completed in 97 (100%) donors. No conversion to open operation occurred among the HLDN group. The mean (standard deviation) operative durations were 157.92 (23.79) minutes for HLDN and 103.21 (19.63) minutes for ODN (P = .000), and hospital stays were 5.00 (1.54) days for the HLDN group and 6.59 (0.79) days for the ODN group (P = .000). There was no significant difference between the 2 groups in postoperative donor (P = .541) and recipient (P = .337) renal functions. The primary reason encouraging donors was family obligations and bonds (70.1%); the availability of HLDN did encourage the decision (29.9%). Although all renal donors were aware of the option of HLDN, 28 selected ODN because of financial reasons, another 4 patients due to safety concerns. The main reasons for choosing HLDN instead of ODN were less postoperative pain (60%) and cosmetic concerns (29.2%).

Conclusions: HLDN was safe and feasible to procure a normally functional organ for live donor transplantation. The availability of the HLDN approach did affect a donor`s decision. The main reason for choosing HLDN instead of ODN was less postoperative pain.
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