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Articles by G. Archunan
Total Records ( 2 ) for G. Archunan
  S. Alagendran , G. Archunan , K. Rameshkumar , B. Kadalmani , Jorge Arturo de Leon Rodriguez , Gabriela Fernandez , G. Martinez and Rosalinda Guevara Guzman
  Problem statement: The present investigation carry out a pilot study of a novel method to identify the salivary volatiles in different phases of menstrual cycle for the assessment of ovulation detection using gas chromatography and mass spectrophotometer. Approach: The profiles from follicular phase (6-12 days); ovulatory phase (13-14 days) and luteal phase (15-26 days) of menstrual cycle samples were compared to establish any qualitative and quantitative differences that might have potential value in human olfactory communication. Dichloromethane was used as the solvent for extraction of the compounds. Results: Fifteen compounds were identified. They include organic compounds like, acid, aldehyde, amine and alcohol. The most important constituent was 2-nonenal, which usually comprised 75% or more of the total volatiles observed in ovulatory phase. The concentration of many constituents varied widely. This appeared to be periodically in three cycles for five of the constituents, with a period of a few weeks and with pronounced maxima at the peak of ovulatory period of which only two were common to all the chromatograms. The chemical profile of ovulatory phase saliva was distinguished by the presence of two specific compounds, viz. 2-Nonenal, Acetic acid and Acetaldehyde that were not found in the other reproductive phases of saliva sample in women. Apparently these compounds are 2-nonenal, dodecanol, acetic acid and acetaldehyde. One or more of these compounds may have pheromonal activity in human body odor. Conclusion: Differentiation of the volatile patterns among reproductive phases in women may help to find the diagnostic marker for ovulation detection.
  K. Rajesh , K.C. Padmavathi , A. Ranjani , P.M. Gopinath , D. Dhanasekaran and G. Archunan
  The silver nanoparticles (AgNPs) were synthesized using extracellular metabolites of Streptomyces sp. GRD (JX512257). The characterization of the synthesized AgNPs was performed by UV-VIS spectrophotometer, FT-IR, Scanning Electron Microscopy (SEM) and X-ray diffraction spectroscopy. The synthesised silver nanoparticles have maximum absorption at 450 nm in UV-VIS spectrophotometer. The FTIR data showed prominent peak in 3401.33, 2922.30, 2364.79, 2116.07, 1643.17, 1375.53, 1424.69 and 1324.03 cm-1 ranges. The SEM analysis showed that the AgNPs were spherical and slightly elongated in nature. The XRD peaks revealed the crystalline nature of the silver nanoparticles and the size of the synthesized nanoparticles was found to be in the range of 10-15 nm. The biologically synthesized silver nanoparticles were treated against the mosquito larvae of Culex quinquefasciatus and Aedes aegypti. The LC50 value of synthesized nanoparticle was identified as 1.23 and 1.19 mg L-1 for Culex quinquefasciatus and Aedes aegypti larvae. Further, LC90 values are also identified as 2.97 and 4.93 mg L-1, for Culex quinquefasciatus and Aedes aegypti respectively. Hence the present work suggests that the nanoparticles from Streptomyces sp. GRD would be appropriate for developing a biological control method of mosquito larval population.
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