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Articles by Funda KIRAL
Total Records ( 4 ) for Funda KIRAL
  Ulvi Reha Fidanci , Hidayet Yavuz , Cavit Kum , Funda Kiral , Mehmet Ozdemir , Selim Sekkin and Ayhan Filazi
  It was aimed to evaluate the effects of accumulated ammonia (NH3) concentration in poultry housing and Nitrite (NO2-) Nitrate (NO3-) concentrations in poultry litter on thyroid hormone levels (Triiodothyronine (T3) and Thyroxine (T4)), Body Weight (BW) and variables parameters such as blood methemoglobin, serum retinol, β-carotene and total cholesterol levels. Weighing 58.0±3.2 g (control group) and 60.0±4.3 g (experiment group), 1 day old, 180 male broiler chickens were used. Chicks were allowed ad libitum access to feed and water throughout the 45 days trials. In the experiment group, the ventilation was restricted without changing other conditions. NH3 concentration in poultry housing and moisture ratio, as well as NO2--NO3- concentrations in litter were measured with 5 days intervals throughout the 45 days trials. Plasma total T3, T4, blood methemoglobin and serum retinol, β-carotene and total cholesterol levels were evaluated at the 45 days. NH3 concentration in poultry housing was increased after 21 days (p<0.05) at 0.222 g bird-1 day and 26 days (p<0.01) at range 0.377-0.400 g bird-1 day in the experiment group as compared with the control group throughout the 45 days trials. In addition, moisture ratio in litter were increased after 26 days (p<0.05) at 0.444% bird-1 day and 36 days (p<0.01) at range 0.461-0.472% bird-1 day. Also, NO2- concentrations in litter were increased after 26 days (p<0.05) at range 7.50-8-40 ppm bird-1 day. As to NO3- concentrations in litter in the experiment group, no statistically significant difference was observed. Compared to control group, at 45 days, BW, plasma total T3, as well as serum retinol and β-carotene levels decreased significantly in experiment group (p<0.01). Total cholesterol level was increased (p<0.05). No statistically considerable differences were found in plasma total T4 and blood methemoglobin levels.
  Ilker Serin , Gunes Serin , Murat Yilmaz , Funda Kiral and Ahmet Ceylan
  The purpose of this study was to determine the relationship between pregnancy rate and body weight, Body Condition Score (BCS), age, lactation, serum triglyceride, cholesterol and paraoxanase levels of Saanen goats in breeding season. Data were obtained from 55 Saanen does under kept semi-extensive conditions. For estrus synchronization, vaginal sponges containing 40 mg Fluorogestone Acetate (FGA) were applied for 14 days and 500 IU equine gonadotropin hormone (eCG) was injected on the day of vaginal sponges removed. Blood samples were collected from vena jugularis also body weights, body condition scores (5-point scale), ages and lactation status of all goats were recorded at the time of sponges removed. Estrus detection was performed with teaser buck at 48 h after removal of the sponges. All does in estrus were mated with fertile bucks. After 12th day of post-mating, 4 μg gonadorelin was injected intramuscularly for enhance luteal function. Pregnancy diagnosis was performed by transrectal ultrasonography at 40th day of post-mating. The relationship between pregnancy rates and body weight, BCS, age, lactation, blood triglyceride, cholesterol and paraoxanase levels at mating day were statistically analyzed. The body weight and BCS were significantly effected the pregnancy rates (p<0.05) but there were no relation between pregnancy rate and other parameters (p>0.05). It is concluded that body weight and BCS has a significant effect on fertility of Saanen goats during breeding season and the necessity of using higher energy feeding in goats with lower BCS and weight before breeding season.
  Hasan Aksit , Kamil Seyrek , Funda Kiral , Pinar Alkim Ulutas and Turgut Sekerler
  Diabetes is an increasing worldwide health problem. It is well known that diabetes causes brain damage. The mechanism by which diabetes increases brain damage is still elusive. The objective of this study was to determine the effects of streptozotocin-induced diabetes on rat brain tissue. Twenty rats were divided into control and experimental groups at random. In experimental animals diabetes was induced by intraperitoneal injection of a single 50 mg kg-1 dose of streptozotocin while the animals in control group received sodium citrat buffer. Induction of diabetes with streptozotocin resulted in a statistically significant increase in the glucose and malondialdehyde levels whereas ascorbic acid concentrations and Total Antioxidant Status (TAS) decreased significantly in these animals. Compared to the control animals hyperglycemia induced apoptosis in brain tissue of experimental rats significantly. In conclusion, in streptozotocin induced hyperglycaemia in diabetic rats leads to oxidative stress and induce apoptosis in brain tissue. In addition, increased rate of apoptosis might be due to elevated concentrations of reactive oxygen species.
  Kamil SEYREK , Hakan ERBAS , Mukadder SERTER , Cigdem YENISEY , Funda KIRAL and Husnu Erbay BARDAKCIOGLU
  A considerable body of data exists regarding the role of vitamin C in mammalian physiology; however, there are no data about the effects of dietary ascorbic acid supplementation on collagen concentrations and amino acid levels in animals exposed to heat stress. The present study investigated the effects of supplementary ascorbic acid intake on collagen concentrations in the brain and heart tissue in Japanese quails. In addition, glycine, glutamine, histidine, asparagine, and serine contents in the livers of the same animals were measured. Japanese quails were allocated into 4 groups, each of which was exposed to heat stress (34.8 ± 1.25 °C) for 75 days. Control animals were fed a basal diet, while animals in the experimental groups were fed a basal diet supplemented with 150, 250, or 500 mg of L-ascorbic acid kg-1 of diet. Compared to the control group, mean collagen concentration in brain tissue significantly (P < 0.05) increased only in Japanese quails given 250 mg of L-ascorbic kg-1 of diet. On the other hand, heart tissue collagen content in the quails fed vitamin C did not significantly increase; in fact, the collagen content in the group fed 500 mg of L-ascorbic acid kg-1 of diet significantly decreased (P < 0.01). Amino acid content in the liver significantly increased in the group fed 150 mg of L-ascorbic acid kg-1 of diet (P < 0.01 for serine and P < 0.001 for the others).
In conclusion, vitamin C had profound effects on collagen synthesis and amino acid metabolism in Japanese quails subjected to heat stress. Results of the present study also indicate that addition of high-dose dietary vitamin C-higher than 250 mg kg-1 of diet-may have detrimental effects in quails exposed to heat stress.
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