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Articles by Farman Ali Siyal
Total Records ( 2 ) for Farman Ali Siyal
  Farman Ali Siyal , Mohamed Ezzat Abd El-Hack , Mahmoud Alagawany , Chao Wang , Xioli Wan , Jintian He , Mingfa Wang , Lili Zhang , Xiang Zhong , Tian Wang and Kuldeep Dhama
  Background and Objective: Lecithin is a feed supplement and dietary source of several active compounds; therefore, this study evaluated the Soybean Lecithin (SL) in broiler diets by measuring performance, nutrient utilization, serum parameters and hepatic antioxidant status. Methodology: About 216 days old Arbor Acre broiler chicks were allotted into three groups as follow: the first group was fed a Basal Diet (BD) without emulsifier; the second and third groups were fed basal diet supplemented with 0.05 (SL0.05) and 0.1% (SL0.10) of SL, respectively. Results: During starter, grower and overall period, chicken fed with SL has better daily gain and feed intake compared with control, while feed conversion was improved in SL0.10 throughout the experiment compared to SL0.05 and control. At 21 and 42 days old, SL0.10 showed highest relative liver weight compared to SL0.05 and control (p<0.05). On day 21, digestibility of dry matter, ether extract and protein in chickens fed diet with SL0.10 was significantly improved in comparison with those fed SL0.05 and control. Cholesterol, triglyceride and low density lipoprotein concentrations were decreased in SL0.10 group in comparison with control. Serum glucose was higher in SL0.10 group compared to SL0.05 and control. Feeding SL0.10 resulted in the decreased hepatic malondialdehyde content and remarkably increased catalase, total superoxide dismutase and total antioxidant capacity enzyme activities. Conclusion: Feeding soy lecithin at 0.10% improved performance, reduced cholesterol and triglyceride, LDL-cholesterol concentrations in serum broilers. In addition, soy lecithin is suitable for improving antioxidant status and has ability to protect against oxidative stress.
  Umair Muhammad , Xiaoyu Zhu , Zhaoxin Lu , Jinzhi Han , Jing Sun , Sultana Tayyaba , Benazir Abbasi , Farman Ali Siyal , Kuldeep Dhama and Jabbar Saqib
  Background and Objective: Vine tea (Ampelopsis grossedentata) may potentially perform multiple pharmacological roles, including antibacterial, anti-cancer, antioxidant, hepatoprotective and anti-hypertension functions. But effects of extraction polarity, time and temperature on the recovery of bioactive compounds along their pharmacological activity of vine tea extract have not been reported yet. The present study reports on the importance of extraction variables for obtaining vine tea extract aiding in purification and isolation of functional and polyphenolic compound and their pharmacological activity (polyphenols) from vine tea. Materials and Methods: The effects of extraction variables (time, temperature and polarity) on Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and Condensed Tannin Content (CTC) were evaluated using single factor experiment. Antiradical capacity assay and radical-scavenging capacity 2,2-diphenyl-1-picrylhydrazyl (DPPH) were tested for evaluating the antioxidant activities of vine tea crude extract. To analyze data, one-way analysis of variance (ANOVA) was established followed by the Tukey’s test and to test the correlation, Pearson correlation coefficient was tested. Results: Data explained that extraction polarity, extraction time and the temperature had a significant effect (p<0.05) on yield and their anti-radical activities. The optimized extraction parameters for TFA and CTC were 40% aqueous ethanol at 45 while 50 for TPC for 180 min. Whereas, maximum yield were 40.01 μg Catechin Equivalent per gram (CE g–1) of Dry Weight (DW) for TFA, 15.12 μg, Gallic Acid Equivalent per gram of DW (GAE g–1) for TPC and 12.70 μg CE g–1 DW for CTC. Ethanol concentration showed a significant effect (p<0.05) on extraction of phenolic compounds and their pharmacological activity especially antioxidant capacity and DPPH assay. Conclusion: This study showed that extraction variables were greatly influence on the pharmacological activities of vine tea crude extract and this study can be used as preliminary and key information to design central composite rotatable design for Response Surface Methodology (RSM). Moreover, this approach can be used to determine significant factors that influence functional compounds and their other pharmacological activities.
 
 
 
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