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Articles by Faez Firdaus Jesse Abdullah
Total Records ( 3 ) for Faez Firdaus Jesse Abdullah
  Faez Firdaus Jesse Abdullah , Abdinasir Yusuf Osman , Lawan Adamu , Zunita Zakaria , Rasedee Abdullah , Mohd Zamri-Saad and Abdul Aziz Saharee
  Pasteurella multocida is an opportunistic pathogen with veterinary and human significance. The species diverse and complexity between the types exist with respect to antigenic variation, host predilection and pathogenesis. The aim of the present study was to determine hematological and serum concentration of biochemical values in calves having infected with Pasteurella multocida type B and its immunogens; Lipopolysaccharide (LPS) and Outer Membrane Protein (OMP). A total of eight clinically healthy calves were divided into four groups of 2 calves in each group. Group 1 were inoculated with sterile Phosphate Buffered Saline (PBS). Group 2 were inoculated with wild-type P. multocida type B: 2 while Group 3 and 4 were inoculated with LPS and OMP extracted from Pasteurella multocida type B, respectively. Blood samples were collected for haematological and biochemical analysis. Results indicated significant differences in the mean values of Prothrombin Time (PT), Partial Thromboplastin Time (PTT) and thrombocyte levels in infected groups 2-4 compared to the control group. There was significant decrease in the mean concentration of Alanine Transaminase (ALT) for group 2 (20.607±1.639 U L-1), group 3 (22.067±1.617 U L-1) and group 4 (40.327±8.351 U L-1). Conversely, there was no significant difference in Alkaline Phosphatase (ALP) for group 2 (149.857±17.327 U L-1) but a significant decrease for groups 3 (114.147±20.901 U L-1) and group 4 (128.971±17.068 U L-1). There was no significant differences in the serum levels of Gamma-glutamyltranspeptidase (GGT) and almost all tested electrolytes in infected groups. In conclusion, our results provide evidence in support of using some haematological and biochemical markers for early detection of individuals at risk for wild type of Pasteurlla multocida.
  Abdinasir Yusuf Osman , Faez Firdaus Jesse Abdullah , Abdul Aziz Saharee , Abd Wahid Haron , Jasni Sabri and Rasedee Abdullah
  Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis, a chronic infectious disease of sheep and goats. Despite the growing interest of this organism, little is known about the causality and effect of this organism on haematological and biochemical values. The purpose of this research, therefore was to determine haematological and serum biochemical features in mice inoculated with whole bacterium and exotoxin (PLD) extracted from C. pseudotuberculosis. The study was performed on apparently healthy mice of 2-3 weeks old (n = 64). The mice were divided equally into 3 groups; namely whole bacterium, exotoxin (PLD) and control group. Mice of whole bacterium group were exposed intraperitoneally to 1 mL of the inoculums containing 109 Colony-Forming Unit (CFU)/mL of live C. pseudotuberculosis. Exotoxin group were exposed intraperitoneally with a single dose of exotoxin (PLD) extracted from C. pseudotuberculosis. Mice served as a control group were challenged intraperitoneally to 1 mL of Phosphate-Buffered Saline (PBS), pH 7. Following post-infection, the mice were subjected for blood sample collection using cardiac puncture method for haematological and biochemical analysis. The results of this study revealed that there were significant decrease (p<0.05) in Hb, thrombocytes count and significant increase in WBC, neutrophils, monocytes counts in the infected group. Biochemically, there were highly significant increase (p<0.05) in the mean levels of CK, AST, ALP and ALT. The mean level of albumin in exotoxin group was significantly lower (p<0.05) compared to C. pseudotuberculosis and control groups while globulin level was significantly higher in C. pseuodotuberculosis group after 48 h. In serum electrolytes, mean level of potassium and phosphate were significantly (p<0.05) higher in infected groups compared to control group while there was no significant (p<0.05) difference in the levels of sodium, calcium and chloride. In conclusions, the present study of experimental nature showed that C. pseudotuberculosis and its exotoxin (PLD) cause disturbances in blood factors and electrolytes and pointed out that t hese haematological and biochemical alterations should be taken into account in the context of diagnosis and treatment of valuable infected hosts in order to prevent further consequences.
  Nur Hardy bin Abu Daud , Nwe Nwe Htin , Farah Hanif Paan , Than Kyaw , Aung Tun Khaing , Yusuf Abba and Faez Firdaus Jesse Abdullah
  Escherichia coli is one of the most economically important bacteria responsible for early chick mortality in poultry farms worldwide. In this report, researchers investigated a case of sporadic mortality (15%) in 15-18 days old cobb 500 broiler chicks. The chicks were weak with respiratory distress and non-uniform growth rate. Postmortem examination showed evidence of polyserositis with fibrinous hepatitis, pericarditis, peritonitis and air sacculitis as the major findings observed. Bacteriological culture of affected organs showed evidence of E. coli growth on blood agar. The bacteria was found to be resistant to amoxicillin, clindamycin, streptomycin and trimethroprim while intermediate susceptibility to oxytetracyclin and susceptibility to gentamycin were equally observed. The chicks were treated with gentamycin (5-10 mg kg-1 orally) for 5 days and multivitamin (5 g L-1) was given in drinking water for 3 days. Prompt diagnosis and treatment of cases of colibacillosis is crutial to ensuring optimal productivity in poultry farms.
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