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Articles by F.X. Etoa
Total Records ( 2 ) for F.X. Etoa
  C.A. Pieme , J.P. Dzoyem , F.A. Kechia , F.X. Etoa and V. Penlap
  In order to valorise the pharmaceutical potential of natural products, 10 plants of nine different families collected on ethnobotanic informations around Yaoundé in Cameroon were extracted. Seventeen organic and hydro-organic extracts were tested for their biological effects. The in vitro evaluation of antibacterial and antifungal activity was carried out by the well agar diffusion method on seven Gram positive and Gram negative bacteria (P. aeruginosa, E. coli, S. faecalis,S. choelera, P. mirabilis and M. morganii) and two groups of fungi (Filamentous, Yeast). The results showed that 12 of the 17 extracts demonstrated antibacterial activity against the seven pathogenic bacteria tested. The growth inhibition halos were ranged from 8.00 to 32.33. Among them, extracts of Solanum aculeastrum (Solanaceae) and Syzygium guinensis (Myrtaceae) showed the higher antibacterial activity. For the antifungal activity, growth inhibition halos varied from 8.00 to 17.55 mostly against Geotrichum candidum and Penicillium species. The extracts S. aculeastrum demonstrated antibacterial and antifungal activity.
  P. Bogne Kamga , G.L. Tiani Mouthe , B. Ouahouo Wache , V. Penlap Beng , F.X. Etoa and A.E. Nkengfack
  The present study was designated to evaluate the antibacterial activities of the ethyl acetate crude extract and their secondary metabolites isolated from the twigs of Hypericum roeperanum. This plant is used as traditional folk medicine in Cameroon for the treatment of infectious diseases and gastrointestinal disorders. The antibacterial activities of the extract and their secondary metabolites against ten pathogens causing gastrointestinal disorder were tested using disc diffusion method. The inhibition parameters were determined using microdilution method. The results showed that ethyl acetate crude extract exhibited a significant antibacterial effect against all the strains studied. This activity is the results of the presence of 1,3,5,6-tetrahydroxyxanthone (Norathyriol) and 2,5-dihydroxyxanthone isolated from the plant using repeated column chromatography of the ethyl acetate crude extract. These compounds exhibited a significant antibacterial effect against all the strains studied. However, betulenic acid, 5,7,3,4-tetrahydroxyflavanone, 1,7-dihydroxyxanthone, 5-hydroxy-2-methoxyxanthone, 1,3,6,7-tetrahydroxyxanthone, lupeol, friedelin and friedelinol eight other compounds isolated from this plant were inactive. The ratio of the minimal bactericidal concentration over the minimal inhibition concentration indicates the bactericidal effect of the plant.
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