Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by F.O. Shode
Total Records ( 1 ) for F.O. Shode
  J.D. Habila , F.O. Shode , G.I. Ndukwe , J.O. Amupitan and A.J. Nok
  Background: Natural product compounds are the source of numerous chemotherapeutic agents. Investigations were carried out to evaluate the therapeutic properties of a C-3 modified oleanolic acid, 3β-acetoxyoleanolic acid (JH23), in the continue search for lead compounds. Results: The well-in-plate agar diffusion method used for the inhibition zone determination, showed that compound JH23 had a more enhanced activity as compared to JH16 (oleanolic acid) the parent nucleus, on most of the test organism; Candida guielemondi (JH23, 23±0.04; JH16, 22±0.03), Candida albicans (JH23, 29±0.05; JH16, 21±0.12), Candida krusei (JH23, 26±0.04; JH16, 23±0.001), Candida tropicalis (JH23, 30±0.02; JH16, 23±0.01), Trichophyton tonsurans (JH23, 29±0.03; JH16, 19±0.02) and Microsporum canis (30±0.01; JH16, 16±0.04). Conclusion: The results showed that functionality modification of organic compounds could lead to compounds with enhanced bioactivity.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility