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Articles by Effat Merghati Khoei
Total Records ( 2 ) for Effat Merghati Khoei
  Neda Shams Alizadeh , Effat Merghati Khoei , Mehrdad Fazelimanesh and Ahmad Astaneh
  According to increased bacterial resistance to common antibiotics, tendency toward using herbal drugs is increasing. Many researches have been executed about antibacterial and preservative effects of herbal extract like extracts of lamiacceae family (like Shiraz oregano herb). In this study, anti microbial effects of Zataria multiflora extract on Urinary Tract E. coli Infections in comparison with eleven antibiotic disks in antibiogram pattern is evaluated. After providing microbe suspension and comparing it to Mc Farland 0.5 to obtain 1.5x108 bacterium per milliliter the susceptibility of the mentioned bacteria was determined in Muller-Hinton agar by embedding the disks of Betadine, Zataria multiflora and antibiotic disks. Fallowing incubation of media for 24 h at 37°C the inhibition zone of Zataria, Betadine and antibiotic disks were measured. Surprisingly, according to antibiogram results, the most sensitivity of E. coli was to Z. multiflora extract and inhibitory zone produced by eleven antibiotic disks and betadine are significantly less than Zataria induced. According to obtained results and limitations of increasingly usage of chemical antimicrobial substances there is a need to replacement of these substances with natural and herbal extracts.
  Neda Shamsalizadeh , Effat Merghati Khoei , Fatemeh Sheikhan and Mehrdad Fazelimanesh
  Urinary Tract Infections (UTIs) are considered when pathogens gain access from urethra to upper parts of urinary tract and cause infections. Evaluation of the anti-microbial activity of Zataria multiflora in comparison with antibiotic disks against urine isolates of Staphylococcus aureus is the aim of this study. Microbe suspension equal to Mc Farland 0/5 was prepared and then bacterial strains were transferred to the surface of Muller-Hinton agar with a swab and the susceptibility of the mentioned bacteria was determined by embedding the disks of antibiotics, Zataria multiflora and Betadine (10%), fallowing incubation of the media the inhibition zone around disks were measured. According to antibiogram results, the inhibition zone produced by Zataria multiflora was more than antibiotics and Betadine and it was sensitive in all experiments even in cases that there were no sensitive antibiotics. This comparison showed potential efficiency of anti-Staphylococcus aureus activity for Zataria multiflora and a significant difference between its antimicrobial activity and antibiotics disks obtained. According to increase of drug resistance, further investigations are needed to determine that if it can be useful in management of urinary tract Staphylococcus coagulase positive infections especially when there is no sensitive antibiotic.
 
 
 
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