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Articles by E.O. Dada
Total Records ( 1 ) for E.O. Dada
  M.K. Oladunmoye and E.O. Dada
  Ethanolic leaf extract from Aframomum melegueta was accessed for in vitro antimicrobial activity as well as phytochemical constituents. Refuse dump materials were screened for resident micro floral with antagonistic activities against the pathogens. Thirteen pure isolates were obtained in all including nine bacteria and four fungi. Five pathogenic bacteria; Bacillus cereus, Staphylococcus aureus, Escherichia coli, Salmonella typhi and Klebsiella pneumoniae were tested for their susceptibilities to the antimicrobial activity of the leaf extract as well as the antagonistic potential of the isolates refuse Standard antibiotics were also tested on the pathogens and their susceptibilities investigated. The effectiveness of the antimicrobial phytoconstituents from Aframomum melegueta and microbial antagonisms was compared with that of the standard antibiotics in which the former fairly compete with the latter. The plant extract of Aframomum melegueta was found inhibitory to the growth of Salmonella typhi and Klebsiella pneumoniae while the refuse isolates were more effective than the bacteria as shown growth inhibitory indices. Seven of the nine isolates inhibited the growth of at least one of the pathogenic organisms; Klebsiella pneumoniae and Staphylococcus aureus being the most susceptible. The findings revealed that the extract from the plant and the refuse isolates offer an enormous potential as biocontrol of these pathogens and source of antimicrobial agent of therapeutic importance.
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