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Articles by E. Jeroh
Total Records ( 4 ) for E. Jeroh
  E. Jeroh , E.P. Awhin , L. Osademe and E.I. Awire
  The effect of carbonated drink also known as pop soda was studied in this research. The aim of this study was to check the possible effect on the activities of the kidney biomarkers [alanine aminotransferase (ALT) and aspartate aminotransferase (AST)] in Rattus novergicus. The results from this study revealed that the activities level of serum ALT of group A (24.1±5.8) showed a significant increase at (p<0.05) when compared with that of the control C (10.0±2.72) while that of group B (1.75±1.66) showed a significant decrease in enzyme activity when compared with that of the control. It was also revealed that there was significant increase in AST enzyme activity in brand B (24.2±6.38) when compared with that of the control C (17.0±1.94) at (p<0.05). The result from the investigation of kidney ALT and AST activities showed that there was a slight increase in AST activity with brand B (17.70±1.68) when compared with that of the control (16.70±2.52) at (p>0.05), While the kidney ALT level for brand A and B were reduced when compared with that of the control (p>0.05). The results of the study suggest that over consumption of carbonated drink may cause liver injury thereby increasing the liver enzyme activity, however overconsumption of carbonated drinks may cause problem to the kidney if there is alteration of kidney architecture. The results from the research showed that for healthy kidney, overconsumption of carbonated drinks may have no effect.
  E. Jeroh , N.J. Tonukari and A. Anigboro
  The analysis of soil glucose level and amylase activity in crude oil treated soil following remediation with Poultry Manure (PM) and Sawdust (SD) were studied for four weeks using standard bioremediation techniques. The aim of this research was to analyse the effect of sawdust and poultry manure on the bioremediation of crude oil contaminated soil. Amylase activity was determined by the Richard and Norbert method while glucose was determined by the Barham and Trinder method of analysis respectively. The aim of this study was to determine the role sawdust and poultry manure play in the process of bioremediation of crude oil contaminated soil. The result showed a statistically significant decrease in soil glucose level after bioremediation (p<0.05). The introduction of sawdust, led to increase in soil glucose level on day 14 (0.09±0.222, 0.07±0.242 and 0.08±0.242 (mmol g-1), respectively, while the drop experienced on day 28 may be due to the utilization of available glucose by microorganisms for metabolic activities that led to biodegradation of crude oil. The amylase activity in the soil upon crude oil contamination reduced from 151.40±1.22 to 150.80±1.22 IU g-1. Statistical analysis shows that treatment of crude oil contaminated soil with sawdust and poultry manure increased soil amylase activity (p<0.05). The results of this study suggest that a combination of poultry manure and sawdust in bioremediation of crude oil contaminated soil is a solution to the problem of oil spillage in the Niger Delta region of Nigeria.
  C.A. Alalor , C.I. Igwilo and E. Jeroh
  The assessment of antifungal potential of the aqueous and methanol extracts of sun-dried leaves of Cassia alata was investigated by testing the extracts against some fungi (Candida albicans, Trichophyton mentagrophyte, Aspergillus niger and Penicillium) using the Agar cup plate method. The Minimum Inhibitory Concentration (MIC) of the aqueous extracts against susceptible test organism was determined using the Agar dilution method. The results showed that the plant part can be used to treat infections caused by fungi (Candida albicans, Trichophyton mentagrophyte and Aspergillus niger) which were susceptible. However, results showed that C. alata extract has no effect on Penicillium. The in vitro findings justify the use of the extract of Cassia alata in traditional medicine practice for the treatment of some external skin and fungal infections. Cassia alata has shown to be a very versatile plant and can be a viable alternative as an antifungal agent.
  E. P. Awhin , E. Jeroh , A.A. Anigboro and Nwaoroko Rachael
  The effect of chronic consumption of Piliostigma thonningii on the activities of Aspartate Aminotransferases (AST) and Alanine Aminotransferases (ALT) on serum and liver of Rattus novergicus was investigated in this research. The aim of this study was to check the possible effect of chronic consumption of Piliostigma thonningii on the activities of the liver biomarkers (ALT and AST) in Rattus novergicus. The results from this study revealed that the activities of aspartate aminotransferase (AST) in serum, showed a significant increase (34.20±12.9*) at (p<0.05) upon chronic consumption of ethanolic extract of P. thonningii when compared with that of the control B (18.02±1.54). The result also showed that the liver AST was significantly increased (32.75±5.89*) when compared to that of the control B (17.01±1.81) at (p<0.05). The results from the study also revealed that there was a significant increase in the activity of alanine aminotransferase in the liver (17.01±5.86*) when compared with that of the control B (5.1±1.11) at (p<0.05). There was a corresponding increase in serum activity of the enzyme ALT (13.65±3.79*) when compared with that of the control B (9.4±1.98) at (p<0.05). The results from this research has shown that chronic consumption of P. thonningii may cause liver injury thereby, increasing the liver enzyme activity (17.01±5.86*). This was shown in the corresponding increase in the serum level. Excessive consumption of the extract of P. thonningii has a toxicity potential on the liver and possibly other organs and tissues.
 
 
 
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