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Articles by E. Huq
Total Records ( 5 ) for E. Huq
  S.M.A. Kawsar , E. Huq , N. Nahar and Y. Ozeki
  Extracts of Macrotyloma uniflorum plants were examined as potential sources of phenolic compounds. Reversed phase high performance liquid chromatography (RP-HPLC) with UV detection was employed for the identification and quantification of the phenolic acids. Eight phenolic acids, namely, 3, 4-dihydroxy benzoic, p-hydroxy benzoic, vanillic, caffeic, p-coumeric, ferulic, syringic and sinapic acids were isolated from an ethanolic extract of Macrotyloma uniflorum. The most abundant phenolic acids were p-coumaric acid (8.95 mg 10-2 g of dry sample) and p-hydroxy benzoic acid (7.81 mg/100 g of dry sample).
  S. M.A. Kawsar , E. Huq , N. Nahar and Y. Ozeki
  .
  S.M.A. Kawsar , G. Mostafa , E. Huq , N. Nahar and Y. Ozeki
  The bioactivity guided separation of the dichloromethane extract of the aerial parts of Macrotyloma uniflorum Linn. resulted in the isolation of methyl ester of hexadecanoic and ethyl ester of hexadecanoic acid mixture (I) and n-hexadecanoic acid (II). The structures of the isolated compounds were elucidated by spectroscopic analysis, including UV, IR, 1H-NMR, 13C-NMR and mass spectroscopy. In addition, the fractionated crude extract of 1-butanol exhibited the significant hemolytic activity by using mouse erythrocytes.
  S.M.A. Kawsar , E. Huq and N. Nahar
  The fractionated crude extracts dichloromethane (CH2Cl2), ethyl acetate (EtOAc), 1-butanol (1-BuOH) and aqueous (H2O) from aerial parts of Macrotyloma uniflorum were screened for cytotoxicity using the brine shrimp lethality bioassay technique. Most of the extracts were found to be non-toxic and this indicates that the ethnobotanical use (oral applications) of the experimental plant are justified.
  S. M.A. Kawsar , M. Seraj Uddin , E. Huq , N. Nahar and Yasuhiro Ozeki
  In the present research, attempt was taken to explore the antimicrobial potency of the crude extracts of the Macrotyloma uniflorum plant. The extractives of the plant were subjected to screening for inhibition of microbial growth by the disc diffusion method. The zones of inhibition demonstrated by the dichloromethane, ethyl acetate, 1-butanol and aqueous extracts ranged from 11-16, 10-24, 10-14 and 10-12 mm, respectively at a concentration of 500 μg disc-1. The ethyl acetate extract showed promising antibacterial activities against all the gram-positive and gram-negative bacteria whereas dichloromethane extract showed moderate activities and the 1-butanol and aqueous extracts did not show any significant antimicrobial activities. In addition, the antifungal activities of all the extractives were tested, using the food poisoning technique. Only dichloromethane extract has been proved to be active against all fungi tested with a higher inhibition activity than standard nystatin. The overall results provide promising baseline information for the potential use of the crude extracts from M. uniflorum in the treatment of bacterial and fungal infections.
 
 
 
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