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Articles by D.O. Ehizibolo
Total Records ( 2 ) for D.O. Ehizibolo
  E.A. Ogunsan , A.A. Seawright , D.O. Ehizibolo , H.M. Tukur , M.S. Ahmed , Y.G. Dashe and M.Y. Sugun
  It has become apparent that inflammation provoked by injury to renal epithelial cells serves to amplify kidney injury and dysfunction in vivo Compounds including the sesquiterpene ketones generally believed to cause kidney injury by direct tubular toxicity or crystal nephropathy have been considered in different renal studies. The aim of this study was to highlight the histotoxicity of Deisopropylngaione (DIN) in mice. Ninety male quackenbush mice weighing between 30 and 35 g b.wt. were divided into five groups of fifteen mice per group and received 70, 98, 137, 192 and 268 mg kg-1 DIN intraperitoneally, respectively. Haematoxylin erosin (H and E) and Von Kossa stained histology slides showed proximal tubular necrosis and hyaline cast formation. Deposition of calcium salt in residual necrotic tubular epithelium was on the increase with increase in dose rate. Besides the pulmonary lesions seen in mice following intoxication by DIN, the kidney lesions were consistent with previous studies of these compounds in mice and similar to mercuric chloride poisoning in sheep.
  E.A. Ogunsan , J.K. Ipinjolu , A.I. Daneji , D.O. Ehizibolo , A.U. Junaidu , U.M. Chafe and F.M. Tambuwal
  In an experiment conducted to determine the effect of including Monechma ciliatum (MC) in the diet of rabbit at 0 (control) 10, 20 and 30% levels, the results showed that increasing the level of supplementation of MC beyond 10% decreased feed intake and subsequently live weight gain. Dry matter digestibility also follow similar pattern. The least cost of feed per kilogram (kg) live weight gain of $0.75 also occurred at the 10% inclusion level of MC. Although, blood parameters differed between treatments, they were mostly within physiological limits, suggesting no adverse effects in feeding MC to the animals.
 
 
 
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