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Articles by D.A. Nyam
Total Records ( 2 ) for D.A. Nyam
  J. Ngbede , E.B. Ogundeji , D.A. Nyam and R.E.J. Guktur
  In vitro activity of three members of the macrolide group of antibiotics (Erythromycin, Clarithromycin and Azithromycin) and two members of the fluoroquinolone group of antibiotics (Ciprofloxacin and Ofloxacin) were assessed against Bacillus anthracis by standard tube dilution method. All the isolates showed varied susceptibility to the 2 groups of antimicrobial agents. The isolates were susceptible to Ciprofloxacin (MIC50-0.78 g mL 1) and Ofloxacin (MIC50-0.31 g mL 1) but were resistant to Erythromycin ((MIC50-25 g mL 1), Clarithromycin ((MIC50-31.25 g mL 1) and Azithromycin ((MIC50-200 g mL 1). Comparing the results of the 2 groups of antibiotic susceptibility tests, we do not recommend the use of any of the 3 macrolide antibiotics tested for prophylaxis or therapy of B. anthracis in our geographical area, except with specific result of susceptibility test on the particular isolate(s). Ofloxacin is highly recommended as a good alternative to ciprofloxacin antibiotic.
  J. Ngbede , R.A. Yakubu and D.A. Nyam
  Canarium schweinfurthii (Atile) leaves from Lamingo Area of Jos North Local Government Area of Plateau State were screened for the presence of chemically active compounds by standard methods. The results revealed the presence of the following compounds: Saponins, Tannins, Cardiac glycoside, Steroids and Flavonoid. Alkaloid and anthraquinone were not detected from the leave extract. We recommend further research work on this plant leaves for possible use as a source of raw material for industrial and medical science utilization.
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