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Articles by D. Mohajeri
Total Records ( 2 ) for D. Mohajeri
  B. Amouoghli Tabrizi , D. Mohajeri , G. Mousavi , F. Farajzade , A. Khodadadi , S.B. Alizade and B. Reihani
  In the present research, we decided to study about the protective effect of vitamin E against Azathiprine-induced toxicity. In this study, 40 male Wistar rats were divided to 4 groups (each group contains 10 rats). For the first group, as the control one, normal saline was given. The second and third groups received 20 mg kg-1 of vitamin E daily and for 7 days by Intra Muscular (IM) injection. The forth group, that had similar state with three others, normal saline was injected for 7 days. On the seventh day, both 3 and 4 group treated by 15 mg kg-1 Azathioprine as a single dose and Intra Peritoneal (IP) form. Two other groups only received the dissolvent of Azathioprine in the same dose and manner. Twenty four hours after Azathioprine injection, the animals after being weighted were anesthetized by ether and blood sample were taken via., the tail vein and pathological sample was got from liver. The samples were allowed to clot and then their serum was separated by centrifuge machine of 2500 rpm for 10 min. This study showed that Azathioprine-induced damage on liver in group 3 is less than group 4 and function of organ in group 3 is nearly same with control group. Results of this study demonstrated that vitamin E decrease Azathioprine-induced hepatotoxicity in rat. According to surveys that have done, the necrotic regions and hepatic cellular death in liver was so lesser in the group that treated together with Azathioprine and vitamin E than the group that treated only by Azathioprine and was so similar to control group. Generally, the pathological results of this study confirm the biochemical results.
  D. Mohajeri , A. Rezaie and Gh. Mousavi
  The aim of the present study was to assess the incidence and age distribution of hepatic tumors of sheep as well as study of their histopathologic characteristics. For this purpose, 3000 slaughtered sheep, consisting of 284 rams with approximate age of 7 to 20 months and 2716 ewes with approximate age of 3 to 7 years, were inspected during a routine postmortem examination. This study was conducted at Tabriz abattoir in the East Azerbaijan province of Iran, in a course of 8 months from March to November 2006. In this survey, two livers were encountered tumoral. Representative sections of the tumors were stained with hematoxylin and eosin. Gross and microscopic features of these tumors supported diagnosis of hepatocellular carcinoma and cholangiocellular carcinoma for a seven-years-old crossbreed ewe and a five-years-old native breed ewe respectively. In this survey, 0.074% of slaughtered ewes had hepatic neoplasia. That is, the prevalence of hepatocellular carcinoma and cholangiocellular carcinoma in aged ewes was equally 0.037% in this study.
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