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Articles by D. R Harris
Total Records ( 2 ) for D. R Harris
  S Naar King , J. T Parsons , D. A Murphy , X Chen , D. R Harris and M. E. Belzer

Objective  To determine if Healthy Choices, a motivational interviewing intervention targeting multiple risk behaviors, improved human immunodeficiency virus (HIV) viral load.

Design  A randomized, 2-group repeated measures design with analysis of data from baseline and 6- and 9-month follow-up collected from 2005 to 2007.

Setting  Five US adolescent medicine HIV clinics.

Participants  A convenience sample with at least 1 of 3 risk behaviors (nonadherence to HIV medications, substance abuse, and unprotected sex) was enrolled. The sample was aged 16 to 24 years and primarily African American. Of the 205 enrolled, 19 did not complete baseline data collections, for a final sample size of 186. Young people living with HIV were randomized to the intervention plus specialty care (n = 94) or specialty care alone (n = 92). The 3- and 6-month follow-up rates, respectively, were 86% and 82% for the intervention group and 81% and 73% for controls.

Intervention  Healthy Choices was a 4-session individual clinic-based motivational interviewing intervention delivered during a 10-week period. Motivational interviewing is a method of communication designed to elicit and reinforce intrinsic motivation for change.

Outcome Measure  Plasma viral load.

Results  Youth randomized to Healthy Choices showed a significant decline in viral load at 6 months postintervention compared with youth in the control condition (β = –0.36, t = –2.15, P = .03), with those prescribed antiretroviral medications showing the lowest viral loads. Differences were no longer significant at 9 months.

Conclusion  A motivational interviewing intervention targeting multiple risk behaviors resulted in short-term improvements in viral load for youth living with HIV.

Trial Registration Identifier: NCT00103532

  W Barnes , L D'Angelo , M Yamazaki , M Belzer , S Schroeder , J Palmer Castor , D Futterman , B Kapogiannis , L Muenz , D. R Harris , J. M Ellen and for the Adolescent Trials Network for HIV/AIDS Interventions

Objective  To test whether "venue-based testing" could identify human immunodeficiency virus (HIV) infection in US youth, 12 to 24 years of age, who were otherwise not aware of their infection. Racial and ethnic minority women and men who have sex with men (WSM and MSM) compose the majority of new HIV cases among adolescents and young adults.

Design  Cross-sectional study.

Setting  Selected venues in communities surrounding the 15 Adolescent Trials Network for HIV/AIDS Interventions (ATN) clinical sites over a 3-month period.

Participants  At each venue, ATN sites recruited 20 to 30 English- or Spanish-speaking at-risk youth (12 to 24 years of age), resulting in a total of 1217 study participants, including 611 MSM and 606 WSM.

Intervention  Venue-based HIV testing with 2 components: an anonymous audio computer-assisted self-administered interview and an anonymous HIV antibody assay.

Main Outcome Measure  The prevalence of HIV infection in MSM and WSM.

Results  The prevalence of HIV infection in MSM and WSM was 15.3% and 0.3%, respectively. Sixty percent of the MSM and 100% of the WSM claimed to not know of their infection.

Conclusion  Venue-based testing may be an important strategy to identify HIV-infected younger MSM; however, other strategies are needed for WSM.

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