Articles by Christian Haass (7)

Generation of Aβ38 and Aβ42 Is Independently and Differentially Affected by Familial Alzheimer Disease-associated Presenilin Mutations and γ-Secretase Modulation

Richard M. Page, Karlheinz Baumann, Masanori Tomioka, Blanca I. Perez-Revuelta, Akio Fukumori, Helmut Jacobsen, Alexander Flohr, Thomas Luebbers, Laurence Ozmen, Harald Steiner and Christian Haass

The Journal of Biological Chemistry 283 ( 2 ): 677 - 683 , 2008

Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion

Sunita S. Shankaran, Anja Capell, Alexander T. Hruscha, Katrin Fellerer, Manuela Neumann, Bettina Schmid and Christian Haass

The Journal of Biological Chemistry 283 ( 3 ): 1744 - 1753 , 2008

Regulated Intramembrane Proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

Lucas Martin, Regina Fluhrer, Karina Reiss, Elisabeth Kremmer, Paul Saftig and Christian Haass

The Journal of Biological Chemistry 283 ( 3 ): 1644 - 1652 , 2008

A Novel Sorting Nexin Modulates Endocytic Trafficking and α-Secretase Cleavage of the Amyloid Precursor Protein

Susanne Schobel, Stephanie Neumann, Maren Hertweck, Bastian Dislich, Peer-Hendrik Kuhn, Elisabeth Kremmer, Brian Seed, Ralf Baumeister, Christian Haass and Stefan F. Lichtenthaler

The Journal of Biological Chemistry 283 ( 21 ): 14257 - 14268 , 2008

Intramembrane Proteolysis by γ-Secretase

Harald Steiner, Regina Fluhrer and Christian Haass

The Journal of Biological Chemistry 283 ( 44 ): 29627 - 29631 , 2008

Intramembrane Proteolysis of GXGD-type Aspartyl Proteases Is Slowed by a Familial Alzheimer Disease-like Mutation

Regina Fluhrer, Akio Fukumori, Lucas Martin, Gudula Grammer, Martina Haug-Kroper, Barbel Klier, Edith Winkler, Elisabeth Kremmer, Margaret M. Condron, David B. Teplow, Harald Steiner and Christian Haass

The Journal of Biological Chemistry 283 ( 44 ): 30121 - 30128 , 2008

Chemical Cross-linking Provides a Model of the γ-Secretase Complex Subunit Architecture and Evidence for Close Proximity of the C-terminal Fragment of Presenilin with APH-1

Harald Steiner, Edith Winkler and Christian Haass

The Journal of Biological Chemistry 283 ( 50 ): 34677 - 34686 , 2008