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Articles by Changwei Qiu
Total Records ( 2 ) for Changwei Qiu
  Xian Gao , Lixia Zhou , Ganzhen Deng , Chang Liu , Chengye Li , Changwei Qiu and Xiuli Peng
  To determine which aerobic bacteria exert a marked effect on Cystic Endometrial Hyperplasia-Pyometra complex (CEH-P) and to determine from where these bacteria originate. About 48 privately owned bitches were diagnosed with CEH-P. Healthy vagina and uterine samples were obtained with cotton pledgets and cumulative uterine fluids from CEH-P cysts were collected with a syringe in utero to isolate and identify aerobic bacterial. A total of 99 isolates were identified and the primary aerobe in the CEH-P bitches was found to be Escherichia coli (33/99). The levels of estrode in bitches with endometritis and in bitches with pyometra and estrus were higher than the levels in diestrus bitches (p<0.01). When ranked according to the levels of progesterone in a descending order (i.e., from high to low levels), the ranking was bitches with pyometra, bitches with endometritis, bitches in estrus and bitches in diestrus. These results suggest that in addition to common pathogenic bacteria differential in every area, casual bacterial contamination invariably occurred in bitches with CEH-P and the primary infection ascended from the vagina when the cervix was open. The researchers also inferred that both estrode and progesterone levels in CEH-P bitches were increased relative to the levels in healthy bitches and were even higher than that of the levels observed in estrus bitches. Estrode and progesterone pretreatment and uterine mucosa damage were interpreted as the preconditions for bacterial infection. The hormone levels in CEH-P bitches were similar to the endocrinal characteristics of peripartum bitches.
  Xiuli Peng , Shen Zhang , Ganzhen Deng , Beibei Li , Yue Wu , Mingyue He , Xiao Wang , Chengye Li , Changwei Qiu and Kechun Zhang
  Major histocompatibility complex takes the capital contribution to maternal immune responses to the semiallogenic fetus. As the member of BoLA-Ib, the machenism of class I chain-related genes 2 (MIC2) on pregnant setup and delivery, till remains to be elucidated. To evaluate the possible effect of MIC2 on pregnant establishment and delivery, neonatal ear tissues, fetal placenta, peripheral blood Polymorphonuclear Neutrophils (PMN) of dairy cow in different pregnant stages were collected to analyze MIC2 expression by quantitative RT-PCR. MIC2 on PMN in dairy cows was down regulated expressed in 1st and 2nd trimesters and recoveried back to normal level in peripartum. Moreover, MIC2 was novel upregulated expressed in neonatal ear tissues and downregulated expressed in fetal placenta. These results suggested that MIC2 lowly expressed in the 1st and 2nd trimester of pregnant cows could suppress NKG2D binding MIC2 on PMN and therefore, let embryo escape from maternal immune response. Anabiotic MIC2 expression in peripartum suggested that maternal immune to full grown foetus recover back to normal level which be in favour of delivery. In foetus, novel upregulated expression of MIC2 in tissues was favourible for foetus to escape its autoimmunity. Whereas, downregulated expression in fetal placenta let placenta decoherenced from maternal placentome which was beneficial to delivery.
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