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Articles by Cemal Bulut
Total Records ( 3 ) for Cemal Bulut
  Reyhan Ozturk , Gul R. Yilmaz , Cemal Bulut , Hulya Parpucu , Sami Kinikli , Murat Duranay and Ali Pekcan Demiroz
  Aim:It is demonstrated that in end-stage renal failure without an infectious pathology conventional laboratory parameters such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) or other acute-phase proteins increase non-specifically. We aimed to evaluate procalcitonin (PCT) and other inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis. Materials and methods: A case-control study was conducted in a 600-bed tertiary hospital. Fifty patients with CAPD-related peritonitis constituting the study group and 50 CAPD patients without infection as the control group were included in the study between February 2006 and July 2006. Baseline serum WBC count, PCT, ESR, and CRP levels were determined in all patients.
Results: Fifty-six peritonitis episodes were detected in 50 patients. The mean ESR and CRP levels were significantly higher in the study group (P < 0.001). PCT levels were >0.5 ng/mL in 21 of the 50 patients (42%) in the study group and 8 of the 50 patients (16%) in the control group. The positive predictive value was 100% for CRP levels higher than 5 mg/dL and PCT levels higher than 2 ng/mL. The sensitivities were calculated as 40% and 14% by the same cut-off levels for CRP and PCT, respectively.
Conclusion: Serum CRP level is a significant and valuable parameter for detecting inflammation, and determining a new cut-off point for CRP will increase its usefulness in patients with CAPD-related peritonitis. The sensitivity and specificity of PCT were not superior to CRP in peritoneal dialysis-related peritonitis.
  Zeliha KOCAK TUFAN , Selcan ARSLAN , Salih CESUR , Cemal BULUT , Hasan IRMAK , Sami KINIKLI , Ferah ERGIN , Ali Kutta CELIK and Ali Pekcan DEMIROZ
  The resistant organisms from patients and healthcare workers (HCWs) first colonized the gastrointestinal tract before causing infections in patients. In this study, presence of risk factors for vancomycin-resistant enterococci (VRE) colonization and the prevalence of rectal carriage of VRE among HCWs and hospitalized patients in the absence of an outbreak were investigated. Design: Cross-sectional study. Setting: A 600-bed training and research hospital. Materials and methods: A total of 508 intensive-care unit (ICU) patients and HCWs in these units were included. Risk factors such as previous antibiotic use, especially vancomycin and cephalosporin, the presence of invasive devices like catheters, and co-morbid diseases were investigated. Rectal smear cultures were obtained from each participant to detect VRE colonization. Results: Risk factors for VRE colonization were identified among both patients and HCWs with a significant ratio. Except for one patient, who had been transferred from another hospital, no VRE colonization was detected in patients or HCWs. Conclusion: The result was attributed to factors such as low inter-institutional transfer, HCWs' being free of VRE colonization (transmission is less likely), strict infection control strategy of the hospital, isolation of newly transferred patients suspected of having VRE colonization, isolation of VRE colonization identified patients, use of indwelling catheters only when indicated and their early removal, and low prevalence of predisposing co-morbid diseases and malignity. We want to underline that a strict hospital infection control program can prevent colonization, even in the presence of risk factors.
  Cigdem ATAMAN HATIPOGLU , Ferah ERGIN , Gunay TUNCER ERTEM , Cemal BULUT , Rukiye BERKEM and Ali Pekcan DEMIROZ
  Aim: To determine the immunity of health care workers (HCWs) against measles, rubella, mumps, and varicella infections, and to evaluate the reliability of self-reported history of the disease in predicting immunity. Materials and methods: A self-reported questionnaire was used to obtain the history of the diseases and ELISA to screen specific IgG antibodies. The history of the diseases was compared with serological testing results. Results: Eighty-one HCWs were included in the study. Immunity against measles was 97.5%, rubella 100%, mumps 72.8%, and varicella 96.3%. Positive predictive values of positive histories of the diseases were 100% for measles and rubella, 96.5% for varicella, and 77.4% for mumps. The negative predictive values of the negative/unknown histories were 3.9%, 0%, 3.8%, and 30.0% for measles, rubella, varicella, and mumps, respectively. Conclusion: A positive history of the disease is reliable for predicting the immunity against measles, rubella, and varicella, and vaccination is not required for the HCWs with a positive history. In contrast, a negative/unknown history had no benefit in predicting susceptibility; thus, we consider that these HCWs must be vaccinated according to the serological testing results. For mumps, a decision for vaccination of HCWs can be made by combining the self-reported history and serological testing results.
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