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Articles by C.H. Njoku
Total Records ( 2 ) for C.H. Njoku
  M.T. Adewumi , C.H. Njoku , Y. Saidu , M.K. Abubakar , R.A. Shehu and L.S. Bilbis
  In this study serum copper, chromium and manganese were estimated in 90 diabetic patients attending the outpatient clinic of the Federal Medical Centre, Katsina, an ancient city in North-western Nigeria and the results compared to those of apparently healthy, non-diabetic volunteers of comparable age and social status. Serum glucose level of the diabetic subjects (13.91±2.87 mmol L-1) was significantly (p<0.05) higher that the value obtained for the non-diabetic subjects (4.34±0.11 mmol L-1). The serum levels of Cr (0.19±0.05 μg L-1), Cu (0.42±0.18 μg L-1) and Mn ((1.12±0.24 μg L-1) were significantly (p<0.05) lowered in diabetic subjects. About 75% of the diabetic subjects in the study area had deficient serum levels of these metals. These results suggest that the diabetic patients in the study area have low serum levels of some antioxidant mineral elements. These observations may be an indication that the diabetic subjects are predisposed to increased oxidative onslaught.
  S.O. Bello , B.Y. Muhammad , K.S. Gammaniel , I. Abdu-Aguye , H. Ahmed , C.H. Njoku and U.H, Salka
  The efficacy and tolerability of Solanum melongena and placebo in moderate to Severe asthmatics was evaluated in a randomized, single center, three-arm, triple blind placebo controlled trial in a tertiary hospital setting in Sokoto, Nigeria . The Main outcome measures were weekly disease severity score, daily Salbutamol (Ventolin) inhaler use. Weekly FEV 1 and PEF all expressed as % above baseline and PEF% predicted. Incidence of side effects was the secondary outcome measure. The study revealed significant improvement in all outcome measures over placebo in the two test arm but no significant difference between test arms. At the end of two weeks of daily intake, the dried fruit of Solanum melongena significantly improves asthma symptoms and signs and disease severity score and apparently have a salbutamol sparing effect. No adverse effect was noted.
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